topicAloe Vera Blood Glucose Meta-Analysis
claimPrediabetes is defined as an intermediate metabolic state characterized by impaired fasting glucose and/or impaired glucose tolerance, associated with a high risk of progression to diabetes and vascular dysfunction [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicAloe Vera Blood Glucose Meta-Analysis
claimHowever, long-term use of conventional antidiabetic agents has been associated with adverse effects, reduced tolerance, and diminished efficacy in certain populations [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicAloe Vera Blood Glucose Meta-Analysis
claim12 13 14 15 16 17 18 Aloe vera Evidence from both clinical studies (involving human participants) and preclinical studies (including in vivo and in vitro experimental models) indicates that several herbal medicines exhibit antihyperglycaemic effects through multiple biological mechanisms [,].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicAloe Vera Blood Glucose Meta-Analysis
claim1 2 3 4 5 6 7 8 9 8 10 11 Diabetes mellitus is a persistent metabolic condition characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both [].
evidence level1
citationMuacevic Alexander (2026)
sourceA Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations
topicAloe Vera Blood Glucose Meta-Analysis
claimIts burden increases with age and is amplified by systemic conditions, behavioral risk factors, and socioeconomic disparities.
evidence level1
citationde Molon Rafael Scaf (2026)
sourceDo Adjunctive Therapies with Natural Products Improve Periodontal Clinical Parameters After Non-Surgical Treatment? A Systematic Review and Meta-Analysis
topicAloe Vera Blood Glucose Meta-Analysis
claimThese factors underscore the need for rigorous synthesis of current evidence to clarify their therapeutic relevance and inform future research directions.
evidence level1
citationde Molon Rafael Scaf (2026)
sourceDo Adjunctive Therapies with Natural Products Improve Periodontal Clinical Parameters After Non-Surgical Treatment? A Systematic Review and Meta-Analysis
topicAloe Vera Blood Glucose Meta-Analysis
claimThe cumulative evidence suggests that adjunctive use of natural agents can enhance clinical parameters such as probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, and decreased bleeding on probing (BOP), while also reducing microbial load and inflammatory biomarkers in gingival crevicular fluid or saliva.
evidence level1
citationde Molon Rafael Scaf (2026)
sourceDo Adjunctive Therapies with Natural Products Improve Periodontal Clinical Parameters After Non-Surgical Treatment? A Systematic Review and Meta-Analysis
topicAloe Vera Blood Glucose Meta-Analysis
claim1 2 3 4 5 6 7 1 2 3 4 5 6 7 8 9 10 Porphyromonas gingivalis Tannerella forsythia Treponema denticola Periodontitis is a chronic, multifactorial inflammatory disease characterized by progressive destruction of the tooth-supporting tissues [,,,,,,].
evidence level1
citationde Molon Rafael Scaf (2026)
sourceDo Adjunctive Therapies with Natural Products Improve Periodontal Clinical Parameters After Non-Surgical Treatment? A Systematic Review and Meta-Analysis
topicAloe Vera Blood Glucose Meta-Analysis
claim2021 2020 2020 2017 2020 Diabetes mellitus is common and estimated to be the world’s fastest-growing metabolic disease, associated with chronic hyperglycemia, resulting from defects in insulin secretion, and action, or both (Bilous et al.; Hill-Briggs et al.).
evidence level3
citationAdil Muhammad (2026)
sourceTherapeutic potential of Aloe vera in diabetes mellitus treatment: an update
topicAloe Vera Blood Glucose Meta-Analysis
claimIt also significantly reduced the total cholesterol, triglyceride levels, and low-density lipoprotein (LDL) level, whereas it boosted the high-density lipoprotein (HDL) level at < 0.01 to facilitate the lipid profile metabolism.
evidence level3
citationAdil Muhammad (2026)
sourceTherapeutic potential of Aloe vera in diabetes mellitus treatment: an update
topicAloe Vera Blood Glucose Meta-Analysis
claimOxidative stress was also attenuated due to enhanced glutathione and catalase activities, while decreasing glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), and alkaline phosphatase (ALP) enzymes improved hepatic function at< 0.01 in a dose-dependent approach.
evidence level3
citationAdil Muhammad (2026)
sourceTherapeutic potential of Aloe vera in diabetes mellitus treatment: an update
topicAloe Vera Blood Glucose Meta-Analysis
claimHyperglycemia may exhibit symptoms like polyuria, polyphagia, and polydipsia, while prolonged unmanaged hyperglycemia leads to various complications including cardiomyopathy, angiopathy, nephropathy, and retinopathy (Kazeem et al.; Eckstein et al. ).
evidence level3
citationAdil Muhammad (2026)
sourceTherapeutic potential of Aloe vera in diabetes mellitus treatment: an update