Structured evidence table for Aloe Constipation Meta-Analysis, generated from 3 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Aloe Constipation Meta-Analysis | Irritable bowel syndrome (IBS) is a common disorder of brain-gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. | 1 | Meyer A (2026) | Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome. |
| Aloe Constipation Meta-Analysis | Many IBS patients prefer plant-based preparations to pharmacological therapy; however, the utility of this approach is not well established. | 1 | Meyer A (2026) | Systematic Review and Meta-Analysis: Plant-Based Therapy for Irritable Bowel Syndrome. |
| Aloe Constipation Meta-Analysis | et al., 2023 Bai et al., 2025 Katsumata et al., 2021 Lombardi et al., 2022 Zhong and Liu, 2025 Melanosis coli (MC) is a benign condition commonly found during routine colonoscopy that is characterized by dark brown or black discoloration of the colonic mucosa. | 3 | Zhang Peng (2026) | Role of gut microbiota in melanosis coli: from anthraquinone biotransformation to mucosal homeostasis dysbiosis |
| Aloe Constipation Meta-Analysis | The association between MC and colorectal cancer risk remains a subject of debate. | 3 | Zhang Peng (2026) | Role of gut microbiota in melanosis coli: from anthraquinone biotransformation to mucosal homeostasis dysbiosis |
| Aloe Constipation Meta-Analysis | Available meta-analytic and observational evidence suggests that MC may be associated with increased detection of hyperplastic polyps or adenomas, while a consistent increase in colorectal cancer risk has not been established; therefore, clinical vigilance should be based on the patient’s overall colorectal risk profile rather than on MC alone (;;). | 3 | Zhang Peng (2026) | Role of gut microbiota in melanosis coli: from anthraquinone biotransformation to mucosal homeostasis dysbiosis |
| Aloe Constipation Meta-Analysis | MC is histologically defined by the accumulation of lipofuscin-laden macrophages within the lamina propria of the colon (;). | 3 | Zhang Peng (2026) | Role of gut microbiota in melanosis coli: from anthraquinone biotransformation to mucosal homeostasis dysbiosis |
| Aloe Constipation Meta-Analysis | Furthermore, psyllium has been associated with lower creatinine and uric acid levels, as well as a reduced risk of carcinogenesis. | 4 | Sanlier N (2026) | From Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke. |
| Aloe Constipation Meta-Analysis | Purpose of review This review was conducted to examine the promising health benefits of psyllium, its therapeutic potential in relation to various chronic diseases, its mechanisms, and its possible side effects or toxicity; to explore its applications in food systems; to identify the positive and negative effects of its consumption; and to provide perspectives for future research and development efforts for psyllium. | 4 | Sanlier N (2026) | From Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke. |
| Aloe Constipation Meta-Analysis | Recent findings Psyllium, also known as ispaghula, is a dietary fiber obtained from the shells of Plantago ovata seeds. | 4 | Sanlier N (2026) | From Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke. |
Source documents