Almond LDL Cholesterol Meta-Analysis Evidence Table

Structured evidence table for Almond LDL Cholesterol Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Almond LDL Cholesterol Meta-AnalysisHealth Canada's Quality Appraisal Tool for Intervention Studies was used to assess each study's risk of bias.1Musa-Veloso K (2025)Blood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Almond LDL Cholesterol Meta-AnalysisAlmond consumption significantly reduced LDL-C (-0.132 mmol/L; 95% CI: -0.190, -0.075 mmol/L; p p p p = 0.001), LDL-C:HDL-C (-0.112; 95% CI: -0.199, -0.026; p = 0.011), ApoB (-4.552 mg/dL; 95% CI: -6.460, -2.645 mg/dL; p p = 0.006), with a borderline significant reduction in TG (-0.037 mmol/L; 95% CI: -0.079, 0.005; p = 0.085) and no effects on HDL-C, ApoA, or Lp[a].1Musa-Veloso K (2025)Blood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Almond LDL Cholesterol Meta-AnalysisBackground/objectives While the benefits of almond consumption in reducing levels of TC and LDL-C are well established, the effects on additional lipids that have emerged as important predictors of cardiovascular disease, such as ApoB and the ratio of ApoB:ApoA, are not well characterized.1Musa-Veloso K (2025)Blood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Almond LDL Cholesterol Meta-AnalysisIn this systematic review and meta-analysis, the effects of almond consumption on blood lipids were comprehensively assessed.1Musa-Veloso K (2025)Blood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Almond LDL Cholesterol Meta-AnalysisConversely, a meta-analysis described in a report by the European Food Safety Authority (EFSA) on the tolerable upper intake level for dietary sugars identified a causal relationship with FS and risk of obesity and dyslipidemia from RCTs [].3Peregoy Jennifer A. (2026)The Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
Almond LDL Cholesterol Meta-AnalysisHowever, data from prospective cohorts did not suggest a positive relationship between intake of FS and risk of obesity or dyslipidemia [].3Peregoy Jennifer A. (2026)The Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
Almond LDL Cholesterol Meta-AnalysisFurther, a 2025 meta-analysis of cohort studies found sugar-sweetened beverages (SSB), but not added sugars (nor total sugars), were related to increased risk of type 2 diabetes [].3Peregoy Jennifer A. (2026)The Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
Almond LDL Cholesterol Meta-Analysis1 2 2 The value or threat of added and free sugars (FS) in the diet lacks scientific consensus.3Peregoy Jennifer A. (2026)The Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
topicAlmond LDL Cholesterol Meta-Analysis
claimHealth Canada's Quality Appraisal Tool for Intervention Studies was used to assess each study's risk of bias.
evidence level1
citationMusa-Veloso K (2025)
sourceBlood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicAlmond LDL Cholesterol Meta-Analysis
claimAlmond consumption significantly reduced LDL-C (-0.132 mmol/L; 95% CI: -0.190, -0.075 mmol/L; p p p p = 0.001), LDL-C:HDL-C (-0.112; 95% CI: -0.199, -0.026; p = 0.011), ApoB (-4.552 mg/dL; 95% CI: -6.460, -2.645 mg/dL; p p = 0.006), with a borderline significant reduction in TG (-0.037 mmol/L; 95% CI: -0.079, 0.005; p = 0.085) and no effects on HDL-C, ApoA, or Lp[a].
evidence level1
citationMusa-Veloso K (2025)
sourceBlood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicAlmond LDL Cholesterol Meta-Analysis
claimBackground/objectives While the benefits of almond consumption in reducing levels of TC and LDL-C are well established, the effects on additional lipids that have emerged as important predictors of cardiovascular disease, such as ApoB and the ratio of ApoB:ApoA, are not well characterized.
evidence level1
citationMusa-Veloso K (2025)
sourceBlood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicAlmond LDL Cholesterol Meta-Analysis
claimIn this systematic review and meta-analysis, the effects of almond consumption on blood lipids were comprehensively assessed.
evidence level1
citationMusa-Veloso K (2025)
sourceBlood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicAlmond LDL Cholesterol Meta-Analysis
claimConversely, a meta-analysis described in a report by the European Food Safety Authority (EFSA) on the tolerable upper intake level for dietary sugars identified a causal relationship with FS and risk of obesity and dyslipidemia from RCTs [].
evidence level3
citationPeregoy Jennifer A. (2026)
sourceThe Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
topicAlmond LDL Cholesterol Meta-Analysis
claimHowever, data from prospective cohorts did not suggest a positive relationship between intake of FS and risk of obesity or dyslipidemia [].
evidence level3
citationPeregoy Jennifer A. (2026)
sourceThe Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
topicAlmond LDL Cholesterol Meta-Analysis
claimFurther, a 2025 meta-analysis of cohort studies found sugar-sweetened beverages (SSB), but not added sugars (nor total sugars), were related to increased risk of type 2 diabetes [].
evidence level3
citationPeregoy Jennifer A. (2026)
sourceThe Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis
topicAlmond LDL Cholesterol Meta-Analysis
claim1 2 2 The value or threat of added and free sugars (FS) in the diet lacks scientific consensus.
evidence level3
citationPeregoy Jennifer A. (2026)
sourceThe Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis

Source documents

  1. Blood Lipid Levels in Response to Almond Consumption: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  2. The Impact of Sugar Source on the Relationships Between Free Sugars Intake and Health: A Secondary Analysis