Structured evidence table for Acetyl-L-Carnitine Cognition Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Acetyl-L-Carnitine Cognition Meta-Analysis | Additionally, we performed a risk-of-bias analysis of the studies compatible with the RoB2 tool. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| Acetyl-L-Carnitine Cognition Meta-Analysis | Overall, the risk of bias was high, and the methodological quality was generally low. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| Acetyl-L-Carnitine Cognition Meta-Analysis | Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| Acetyl-L-Carnitine Cognition Meta-Analysis | Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| Acetyl-L-Carnitine Cognition Meta-Analysis | Mendelian randomization (MR) presents a causal inference methodology to examine the effect of modifiable exposure on a disease by leveraging genetic variants to provide evidence of robust associations. | 4 | Luan Sisi (2025) | The Effect of Acylcarnitines on Cognitive Function: A Two‐Sample Mendelian Randomization Study |
| Acetyl-L-Carnitine Cognition Meta-Analysis | S1 Our study adopted the TSMR design, an approach that leverages genetic variants as instrumental variables and utilizes summary statistics from two independent samples, which could minimize confounding and reverse causation and provide more robust evidence for causality. | 4 | Luan Sisi (2025) | The Effect of Acylcarnitines on Cognitive Function: A Two‐Sample Mendelian Randomization Study |
| Acetyl-L-Carnitine Cognition Meta-Analysis | Index SNPs (< 0.01 with any other associated SNPs within 10 Mb) with the lowest‐value were retained. | 4 | Luan Sisi (2025) | The Effect of Acylcarnitines on Cognitive Function: A Two‐Sample Mendelian Randomization Study |
| Acetyl-L-Carnitine Cognition Meta-Analysis | 2020 2019 2015 2021 2011 2014 Cognitive dysfunction is defined as deficits in one or more cognitive domains, including but not limited to memory, executive function, language, and spatial ability (Srikanth et al.). | 4 | Luan Sisi (2025) | The Effect of Acylcarnitines on Cognitive Function: A Two‐Sample Mendelian Randomization Study |
Source documents