What does the evidence say about Watermelon Citrulline Exercise Performance Randomized Trial?

Updated June 2026

Quick Answer

Watermelon Citrulline Exercise Performance Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Background Postmenopausal women are at increased risk of developing cardiovascular, muscular, and metabolic dysfunction due to hormonal changes associated with aging.

Key Takeaways

  • 01Background Postmenopausal women are at increased risk of developing cardiovascular, muscular, and metabolic dysfunction due to hormonal changes associated with aging. [Bahari H (2026)]
  • 02Conclusion Citrulline supplementation may offer benefits for blood pressure regulation (up to 9 mmHg SBP reduction in some studies) in hypertensive postmenopausal women, but evidence for arterial stiffness, endothelial function, and metabolic outcomes remains inconsistent. [Bahari H (2026)]
  • 03Citrulline, a non-essential amino acid and precursor to nitric oxide, has gained interest as a potential dietary supplement for improving vascular health, muscle function, and metabolic parameters in this population. [Bahari H (2026)]
  • 04In conclusion, watermelon juice may benefit individuals engaged in regular exercise by optimizing muscle repair and hypertrophic responses. [Norouzzadeh M (2025)]
The current Migaku evidence database contains 2 reusable source documents for Watermelon Citrulline Exercise Performance Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Background Postmenopausal women are at increased risk of developing cardiovascular, muscular, and metabolic dysfunction due to hormonal changes associated with aging. [Bahari H (2026); evidence level 1] - Conclusion Citrulline supplementation may offer benefits for blood pressure regulation (up to 9 mmHg SBP reduction in some studies) in hypertensive postmenopausal women, but evidence for arterial stiffness, endothelial function, and metabolic outcomes remains inconsistent. [Bahari H (2026); evidence level 1] - Citrulline, a non-essential amino acid and precursor to nitric oxide, has gained interest as a potential dietary supplement for improving vascular health, muscle function, and metabolic parameters in this population. [Bahari H (2026); evidence level 1] - In conclusion, watermelon juice may benefit individuals engaged in regular exercise by optimizing muscle repair and hypertrophic responses. [Norouzzadeh M (2025); evidence level 2] - In the current study, we aimed to assess the impact of watermelon juice as a functional drink on muscle soreness, exercise performance, and muscle hypertrophy. [Norouzzadeh M (2025); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
  2. The Effects of Watermelon Juice on Muscle Hypertrophy, Exercise Performance, and Muscle Soreness in Non-Athlete Men Undergoing Endurance Training: A Randomized Controlled Trial.