What does the evidence say about Tribulus Exercise Performance Randomized Trial?

Updated October 2026

Quick Answer

Tribulus Exercise Performance Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Background High intensity and endurance exercises lead to exercise-induced oxidative stress (EIOS), exercise-induced muscle damage (EIMD), and inflammation, which are the influencing factors on muscle soreness, localized swelling, and sports performance decrease.

Key Takeaways

  • 01Background High intensity and endurance exercises lead to exercise-induced oxidative stress (EIOS), exercise-induced muscle damage (EIMD), and inflammation, which are the influencing factors on muscle soreness, localized swelling, and sports performance decrease. [Nejati M (2022)]
  • 02Therefore, the purpose of this study is to determine the effectiveness of Tribulus terrestris (TT) as an herbal supplement with antioxidant and anti-inflammatory properties on the nutritional, oxidative, inflammatory, and anti-inflammatory status, as well as the sports performance of recreational runners. [Nejati M (2022)]
  • 03Supplement of TT extracts increased serum testosterone levels on male rats,,,,primates, rabbits and castrated rats.Our previous studies demonstrated that TT extracts improved exercise performance of rats with high-intensity endurance trainingand overload trainingby increasing plasma level of testosterone. [Ma Yiming (2017)]
  • 04More clinical trials should be carried out to get a clear conclusion about the effectiveness of TT extracts. [Ma Yiming (2017)]
The current Migaku evidence database contains 2 reusable source documents for Tribulus Exercise Performance Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Background High intensity and endurance exercises lead to exercise-induced oxidative stress (EIOS), exercise-induced muscle damage (EIMD), and inflammation, which are the influencing factors on muscle soreness, localized swelling, and sports performance decrease. [Nejati M (2022); evidence level 2] - Therefore, the purpose of this study is to determine the effectiveness of Tribulus terrestris (TT) as an herbal supplement with antioxidant and anti-inflammatory properties on the nutritional, oxidative, inflammatory, and anti-inflammatory status, as well as the sports performance of recreational runners. [Nejati M (2022); evidence level 2] - Supplement of TT extracts increased serum testosterone levels on male rats,,,,primates, rabbits and castrated rats.Our previous studies demonstrated that TT extracts improved exercise performance of rats with high-intensity endurance trainingand overload trainingby increasing plasma level of testosterone. [Ma Yiming (2017); evidence level 4] - More clinical trials should be carried out to get a clear conclusion about the effectiveness of TT extracts. [Ma Yiming (2017); evidence level 4] - The mobile phase consisted of water containing 0.1% formic acid (A) and acetonitrile containing 0.1% formic acid (B) with the following gradient: 0–1.0 min, 5% B; 1.1–6.0 min linearly increased B from 5% to 20%; 6.1–9.0 min, linearly increased B from 20% to 50%; 9.1–13.0 min, linearly increased B from 50% to 95%; 13.1–18.0 min, 95%. [Ma Yiming (2017); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. The effect of Tribulus terrestris supplementation on inflammation, oxidative stress, and performance of recreational runners: study protocol for a randomized placebo-controlled trial.
  2. Tribulus terrestris extracts alleviate muscle damage and promote anaerobic performance of trained male boxers and its mechanisms: Roles of androgen, IGF-1, and IGF binding protein-3