What does the evidence say about Theanine Executive Function Randomized Trial?

Updated October 2026

Quick Answer

Theanine Executive Function Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: In addition, to investigate whether the single response was associated with cognitive function after regular ingestion, we compared the results of a single-dose and regular ingestion.

Key Takeaways

  • 01In addition, to investigate whether the single response was associated with cognitive function after regular ingestion, we compared the results of a single-dose and regular ingestion. [Baba Yoshitake (2021)]
  • 02A single dose of-theanine reduced reaction time in the attention task and increased correct answers and decreased the number of omission errors in the working memory task. [Baba Yoshitake (2021)]
  • 03α α 29 30 , 31 32 Studies that explored brain activity have previously reported that-theanine intake increases-wave activity.A study by Gomez-Ramirezfound that subjects who ingested 250 mg of-theanine had increased-wave activity for the attention task to be performed. [Baba Yoshitake (2021)]
  • 041 2 3 4 5 6 7 l l l-theanine is a nonproteinogenic amino acid contained in green teaand mushrooms.Among the different tea varieties in Japan, gyokuro and matcha contain more-theanine than sencha.-theanine affects brain functions.Studies in mice indicate that it improves behavior under stress conditions,suppresses deterioration of learning ability under social stress,and improves memory impairment. [Baba Yoshitake (2021)]
The current Migaku evidence database contains 2 reusable source documents for Theanine Executive Function Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - In addition, to investigate whether the single response was associated with cognitive function after regular ingestion, we compared the results of a single-dose and regular ingestion. [Baba Yoshitake (2021); evidence level 2] - A single dose of-theanine reduced reaction time in the attention task and increased correct answers and decreased the number of omission errors in the working memory task. [Baba Yoshitake (2021); evidence level 2] - α α 29 30 , 31 32 Studies that explored brain activity have previously reported that-theanine intake increases-wave activity.A study by Gomez-Ramirezfound that subjects who ingested 250 mg of-theanine had increased-wave activity for the attention task to be performed. [Baba Yoshitake (2021); evidence level 2] - 1 2 3 4 5 6 7 l l l-theanine is a nonproteinogenic amino acid contained in green teaand mushrooms.Among the different tea varieties in Japan, gyokuro and matcha contain more-theanine than sencha.-theanine affects brain functions.Studies in mice indicate that it improves behavior under stress conditions,suppresses deterioration of learning ability under social stress,and improves memory impairment. [Baba Yoshitake (2021); evidence level 2] - The PSQI subscale scores for sleep latency, sleep disturbance, and use of sleep medication reduced after L-theanine administration, compared to the placebo administration (all p p = 0.001 and 0.031, respectively). [Hidese S (2019); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Effects of l -Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study
  2. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.