Structured evidence table for L-Theanine Caffeine Attention Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| L-Theanine Caffeine Attention Randomized Trial | Camellia sinensis 1 2 3 4 5 L-theanine is a naturally occurring, water-soluble, non-proteinogenic amino acid that can be found in the tea plantand some mushrooms (). | 3 | Cotter Jack (2026) | Effects of L-theanine on cognition, mood and sleep: evidence from human trials |
| L-Theanine Caffeine Attention Randomized Trial | In addition, we examine evidence relating to its safety, consider the limitations of the current literature and highlight key areas for future research. | 3 | Cotter Jack (2026) | Effects of L-theanine on cognition, mood and sleep: evidence from human trials |
| L-Theanine Caffeine Attention Randomized Trial | 13 14 13 14 Table 1 13 15 16 17 18 19 There is growing interest among consumers for products that can help to support aspects of cognitive performance, such as attention, decision-making and memory, as well as associated subjective measures like perceived alertness and mental fatigue. | 3 | Cotter Jack (2026) | Effects of L-theanine on cognition, mood and sleep: evidence from human trials |
| L-Theanine Caffeine Attention Randomized Trial | It constitutes up to 50% of the total amino acids in tea and accounts for approximately 1–2% of its dry weight, contributing to tea's characteristic umami flavor (,). | 3 | Cotter Jack (2026) | Effects of L-theanine on cognition, mood and sleep: evidence from human trials |
| L-Theanine Caffeine Attention Randomized Trial | Additionally, previous reports suggest it is associated with health risks, including cardiovascular, respiratory, neurological, immunological, and endocrine-related conditions (;;). | 4 | Kim Jisun (2026) | Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model |
| L-Theanine Caffeine Attention Randomized Trial | If its production is reduced, the body does not receive a strong sleep signal, which makes it harder to fall asleep or to have meaningful sleep rest. | 4 | Kim Jisun (2026) | Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model |
| L-Theanine Caffeine Attention Randomized Trial | Also, chronic sleep deprivation desensitizes the pathways associated with adenosine and impairs sleep recovery, leading to mood and attention deficits (;). | 4 | Kim Jisun (2026) | Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model |
| L-Theanine Caffeine Attention Randomized Trial | Reiter, 2014 Jouvet, 1999 Sleep deprivation has been a topic of interest since the early 1900s. | 4 | Kim Jisun (2026) | Combined Administration of Cannabidiol and L-Theanine Improves Sleep-Related Outcomes in Caffeine-Induced Sleep Disturbances Mouse Model |
Source documents