cognition

What does the evidence say about Theacrine Cognition Randomized Trial?

Updated October 2026

Quick Answer

Theacrine Cognition Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Results Compared to pre-dose, CDT improved performance on the Flanker Test of Inhibitory Control and improved reaction time on the Psychomotor Vigilance Task post-dose.

Key Takeaways

  • 01Results Compared to pre-dose, CDT improved performance on the Flanker Test of Inhibitory Control and improved reaction time on the Psychomotor Vigilance Task post-dose. [Tartar JL (2021)]
  • 02Compared to the placebo, caffeine increased self-reported anxiety whereas the CDT combination increased self-reported alertness. [Tartar JL (2021)]
  • 03Physiological measures suggested that increases in delta EEG power and cortisol production are associated with the effects observed in the CDT condition to optimize certain aspects of egamer performance. [Tartar JL (2021)]
  • 04Background Involvement in video game activities and competitive video gaming (esports) is a rapidly growing field. [Tartar JL (2021)]
The current Migaku evidence database contains 1 reusable source document for Theacrine Cognition Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Results Compared to pre-dose, CDT improved performance on the Flanker Test of Inhibitory Control and improved reaction time on the Psychomotor Vigilance Task post-dose. [Tartar JL (2021); evidence level 4] - Compared to the placebo, caffeine increased self-reported anxiety whereas the CDT combination increased self-reported alertness. [Tartar JL (2021); evidence level 4] - Physiological measures suggested that increases in delta EEG power and cortisol production are associated with the effects observed in the CDT condition to optimize certain aspects of egamer performance. [Tartar JL (2021); evidence level 4] - Background Involvement in video game activities and competitive video gaming (esports) is a rapidly growing field. [Tartar JL (2021); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Learn next

Keep learning from this answer

GuideAshwagandha: What the Evidence Actually Says About Stress and CortisolLegacy library material — check the original sources.GuideMagnesium Glycinate benefits: what does the evidence sayLegacy library material — check the original sources.GuideProbiotics: What the Evidence Actually Supports (and What It Doesn't)Legacy library material — check the original sources.GuideL-Theanine: How It Works, What the Evidence Says, and How to Dose ItLegacy library material — check the original sources.DataTheacrine Cognition Randomized Trial Evidence TableLegacy library material — check the original sources.DataSoy Isoflavones Cognition Randomized Trial Evidence TableLegacy library material — check the original sources.DataLutein Visual Cognition Randomized Trial Evidence TableLegacy library material — check the original sources.

Sources

  1. A Combination of Caffeine, TeaCrine® (Theacrine), and Dynamine® (Methylliberine) Increases Cognitive Performance and Reaction Time Without Interfering With Mood in Adult Male Egamers.