Is Saccharomyces Boulardii Gut Health Randomized Trial safe?

Updated October 2026

Quick Answer

Saccharomyces Boulardii Gut Health Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: boulardii in PCOS women did not affect weight, BMI, or FBS but reduced testosterone and DHEA-S levels.

Key Takeaways

  • 01boulardii in PCOS women did not affect weight, BMI, or FBS but reduced testosterone and DHEA-S levels. [Pourkarim F (2026)]
  • 02Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that affects women during their reproductive age, which may cause infertility. [Pourkarim F (2026)]
  • 03We aimed to evaluate the effect of probiotic supplementation on metabolic parameters and androgen levels in women with PCOS. [Pourkarim F (2026)]
  • 04The aim of this review was to evaluate current evidence regarding the efficacy, safety, mechanisms of action, and clinical applications of probiotic preparations. [Shorabaev E (2026)]
The current Migaku evidence database contains 2 reusable source documents for Saccharomyces Boulardii Gut Health Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - boulardii in PCOS women did not affect weight, BMI, or FBS but reduced testosterone and DHEA-S levels. [Pourkarim F (2026); evidence level 2] - Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that affects women during their reproductive age, which may cause infertility. [Pourkarim F (2026); evidence level 2] - We aimed to evaluate the effect of probiotic supplementation on metabolic parameters and androgen levels in women with PCOS. [Pourkarim F (2026); evidence level 2] - The aim of this review was to evaluate current evidence regarding the efficacy, safety, mechanisms of action, and clinical applications of probiotic preparations. [Shorabaev E (2026); evidence level 4] - Results The reviewed evidence indicates that probiotics may contribute to intestinal homeostasis through modulation of the gut microbiota, enhancement of intestinal barrier function, and regulation of immune responses. [Shorabaev E (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. The Effect of Supplementation with <i>Saccharomyces boulardii</i> in Women with Polycystic Ovary Syndrome: A Double-blind, Randomized Controlled Trial.
  2. Safety and Effectiveness of Probiotic Preparations: A Contemporary Review.