Quick Answer
Phosphatidylserine Cognition Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: This study aimed to evaluate the effects of PS on core symptoms and associated behavioral problems in children with ADHD.
Key Takeaways
- 01This study aimed to evaluate the effects of PS on core symptoms and associated behavioral problems in children with ADHD. [Shen Z (2026)]
- 02In contrast, the PS group demonstrated significant reductions in internalizing (M = 1.83, SD = 3.28, p < 0.05, d = 0.56) and externalizing behaviors (M = 3.38, SD = 5.20, p < 0.05, d = 0.65), whereas the atomoxetine group improved only in externalizing behaviors (M = 2.54, SD = 5.42, p < 0.05, d = 0.47). [Shen Z (2026)]
- 03Phosphatidylserine was not associated with significant improvements in core ADHD symptoms but was associated with reductions in internalizing and externalizing behavioral problems, particularly in reducing aggression. [Shen Z (2026)]
- 04Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children, characterized by attention deficit, hyperactivity, and various internalizing and externalizing behavioral problems. [Shen Z (2026)]
The current Migaku evidence database contains 2 reusable source documents for Phosphatidylserine Cognition Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts.
- This study aimed to evaluate the effects of PS on core symptoms and associated behavioral problems in children with ADHD. [Shen Z (2026); evidence level 4]
- In contrast, the PS group demonstrated significant reductions in internalizing (M = 1.83, SD = 3.28, p < 0.05, d = 0.56) and externalizing behaviors (M = 3.38, SD = 5.20, p < 0.05, d = 0.65), whereas the atomoxetine group improved only in externalizing behaviors (M = 2.54, SD = 5.42, p < 0.05, d = 0.47). [Shen Z (2026); evidence level 4]
- Phosphatidylserine was not associated with significant improvements in core ADHD symptoms but was associated with reductions in internalizing and externalizing behavioral problems, particularly in reducing aggression. [Shen Z (2026); evidence level 4]
- Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children, characterized by attention deficit, hyperactivity, and various internalizing and externalizing behavioral problems. [Shen Z (2026); evidence level 4]
- Phosphatidylserine Supplementation on Psychomotor Speed among Healthy Adults with Subjective Cognitive Declines [Phosphatidylserine Supplementation on Psychomotor Speed among Healthy Adults with Subjective Cognitive Declines (2025); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources