What does the evidence say about Melatonin Sleep Quality Randomized Trial?

Updated July 2026

Quick Answer

Melatonin Sleep Quality Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: While exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations.

Key Takeaways

  • 01While exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations. [Thanawala S (2026)]
  • 02Supplementation with melatonin-SR 2 mg capsule at night for 28 days was found to be effective and safe in improving objective and subjective sleep quality outcomes and overall well-being in the trial population. [Thanawala S (2026)]
  • 03Sleep disturbances and poor sleep quality are growing public health concerns, adversely affecting both physical and mental health. [Thanawala S (2026)]
The current Migaku evidence database contains 1 reusable source document for Melatonin Sleep Quality Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - While exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations. [Thanawala S (2026); evidence level 2] - Supplementation with melatonin-SR 2 mg capsule at night for 28 days was found to be effective and safe in improving objective and subjective sleep quality outcomes and overall well-being in the trial population. [Thanawala S (2026); evidence level 2] - Sleep disturbances and poor sleep quality are growing public health concerns, adversely affecting both physical and mental health. [Thanawala S (2026); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Efficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.