What does the evidence say about Marine Collagen Skin Meta-Analysis?

Updated May 2026

Quick Answer

Marine Collagen Skin Meta-Analysis has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: In HUVECs, GAE increased viability, migration, tube formation, and vascular endothelial growth factor (VEGF) expression.

Key Takeaways

  • 01In HUVECs, GAE increased viability, migration, tube formation, and vascular endothelial growth factor (VEGF) expression. [Jeong S (2026)]
  • 02In mice, GAE accelerated wound closure from day 3 to day 5 and increased granulation/matrix with higher proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) expression after a single topical application. [Jeong S (2026)]
  • 03In addition, keratin 14 (K14) expression was restored in GAE-treated wound tissues, suggesting improved epidermal re-epithelialization. [Jeong S (2026)]
  • 04Marine red algae have been reported to contain a variety of bioactive compounds that are effective in promoting wound-healing processes. [Jeong S (2026)]
The current Migaku evidence database contains 1 reusable source document for Marine Collagen Skin Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation. - In HUVECs, GAE increased viability, migration, tube formation, and vascular endothelial growth factor (VEGF) expression. [Jeong S (2026); evidence level 4] - In mice, GAE accelerated wound closure from day 3 to day 5 and increased granulation/matrix with higher proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) expression after a single topical application. [Jeong S (2026); evidence level 4] - In addition, keratin 14 (K14) expression was restored in GAE-treated wound tissues, suggesting improved epidermal re-epithelialization. [Jeong S (2026); evidence level 4] - Marine red algae have been reported to contain a variety of bioactive compounds that are effective in promoting wound-healing processes. [Jeong S (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of <i>Grateloupia angusta</i> in Cutaneous Wound Models.