Does Magnesium work?

The current Migaku evidence database contains 2 reusable source documents for Magnesium. This answer focuses on strength of evidence and what the studies can or cannot prove. - The evidence of association between magnesium levels and diabetic retinopathy is limited by small study effects. [Kubbara EA (2026); evidence level 1] - Therefore, this systematic review and meta-analysis aim to update the current evidence. [Kubbara EA (2026); evidence level 1] - Sensitivity analysis retained all studies, and no evidence of publication bias was detected. [Kubbara EA (2026); evidence level 1] - Background/objectives Magnesium is an intracellular cation that plays important roles in metabolism and insulin signaling. [Kubbara EA (2026); evidence level 1] - Thus, this review aims to integrate advances in magnesium physiology with contemporary clinical and nutritional evidence, providing a consolidated strategy for understanding the causes, manifestations, diagnosis, and management of hypomagnesemia. [Papagiannidou Anastasia (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.