What does the evidence say about Maca Menopause Randomized Trial?

Updated May 2026

Quick Answer

Maca Menopause Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Background: Middle-aged women frequently experience diverse physical and psychological symptoms, including depression, anxiety, sleep disturbances, vasomotor symptoms, and reduced quality of life, during menopause.

Key Takeaways

  • 01Background: Middle-aged women frequently experience diverse physical and psychological symptoms, including depression, anxiety, sleep disturbances, vasomotor symptoms, and reduced quality of life, during menopause. [Kim JH (2025)]
  • 02Risk of bias was assessed using the Cochrane risk of bias tool, and meta-analyses were performed using a random effects model. [Kim JH (2025)]
  • 03Results: Nonpharmacological interventions significantly reduced symptoms of depression (standardized mean difference (SMD) = -1.10), anxiety (-0.82), sleep disturbances (-0.90), menopausal symptoms (-1.18), and hot flashes (-0.34). [Kim JH (2025)]
  • 04With increasing concerns regarding the side effects of hormone therapy, nonpharmacological interventions have emerged as safer alternatives for symptom management. [Kim JH (2025)]
The current Migaku evidence database contains 2 reusable source documents for Maca Menopause Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Background: Middle-aged women frequently experience diverse physical and psychological symptoms, including depression, anxiety, sleep disturbances, vasomotor symptoms, and reduced quality of life, during menopause. [Kim JH (2025); evidence level 1] - Risk of bias was assessed using the Cochrane risk of bias tool, and meta-analyses were performed using a random effects model. [Kim JH (2025); evidence level 1] - Results: Nonpharmacological interventions significantly reduced symptoms of depression (standardized mean difference (SMD) = -1.10), anxiety (-0.82), sleep disturbances (-0.90), menopausal symptoms (-1.18), and hot flashes (-0.34). [Kim JH (2025); evidence level 1] - With increasing concerns regarding the side effects of hormone therapy, nonpharmacological interventions have emerged as safer alternatives for symptom management. [Kim JH (2025); evidence level 1] - Data synthesis was performed with RevMan 5.4, and the certainty of the evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. [de Aquino ACQ (2025); evidence level 1] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Nonpharmacological Intervention Effects on Middle-Aged Women with Menopausal Symptoms: A Systematic Review and Meta-Analysis.
  2. Pharmacological treatment of antidepressant-induced sexual dysfunction in women: A systematic review and meta-analysis of randomized clinical trials.