Is L-Theanine Anxiety Randomized Trial safe?

Updated May 2026

Quick Answer

L-Theanine Anxiety Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: However, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,].

Key Takeaways

  • 01However, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,]. [Cepeda Uceta Massiel (2026)]
  • 02In a systematic review based on five randomized controlled trials (RCTs), it was concluded that a standardizedextract is an evidence-based treatment option in tinnitus []. [Cepeda Uceta Massiel (2026)]
  • 03Reduced intake of vitamins B12, B6 and B3 may be associated with tinnitus-related annoyance and different studies have shown improvement in symptoms after B-complex vitamins supplementation [,]. [Cepeda Uceta Massiel (2026)]
  • 041 2 3 4 5 6 7 8 Tinnitus, the perception of sound in the absence of an outside source, is a complex multifactorial problem that affects more than 740 million adults globally [] and can be considered a disability when it substantially and persistently impairs daily activities and quality of life []. [Cepeda Uceta Massiel (2026)]
The current Migaku evidence database contains 1 reusable source document for L-Theanine Anxiety Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - However, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,]. [Cepeda Uceta Massiel (2026); evidence level 3] - In a systematic review based on five randomized controlled trials (RCTs), it was concluded that a standardizedextract is an evidence-based treatment option in tinnitus []. [Cepeda Uceta Massiel (2026); evidence level 3] - Reduced intake of vitamins B12, B6 and B3 may be associated with tinnitus-related annoyance and different studies have shown improvement in symptoms after B-complex vitamins supplementation [,]. [Cepeda Uceta Massiel (2026); evidence level 3] - 1 2 3 4 5 6 7 8 Tinnitus, the perception of sound in the absence of an outside source, is a complex multifactorial problem that affects more than 740 million adults globally [] and can be considered a disability when it substantially and persistently impairs daily activities and quality of life []. [Cepeda Uceta Massiel (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study