Quick Answer
Iron Bisglycinate Fatigue Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: In a prospective cross-over stable-isotope absorption trial in young iron-deficient women (n = 52), OatNF reduced with sodium ascorbate carried mainly ferrous iron and showed high fractional absorption with water and with polyphenol-rich food, showing 1.76- and 1.65-fold higher absorption, respectively, compared with ferrous sulfate.
Key Takeaways
- 01In a prospective cross-over stable-isotope absorption trial in young iron-deficient women (n = 52), OatNF reduced with sodium ascorbate carried mainly ferrous iron and showed high fractional absorption with water and with polyphenol-rich food, showing 1.76- and 1.65-fold higher absorption, respectively, compared with ferrous sulfate. [Zhou J (2025)]
- 02Iron fortification can help to treat anaemia, but most current fortificants are limited by low absorption and/or poor sensory properties. [Zhou J (2025)]
- 03Here we introduce oat protein nanofibrils (OatNF) carrying ultrasmall iron nanoparticles that are engineered to carry iron in ferrous or ferric form. [Zhou J (2025)]
The current Migaku evidence database contains 1 reusable source document for Iron Bisglycinate Fatigue Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts.
- In a prospective cross-over stable-isotope absorption trial in young iron-deficient women (n = 52), OatNF reduced with sodium ascorbate carried mainly ferrous iron and showed high fractional absorption with water and with polyphenol-rich food, showing 1.76- and 1.65-fold higher absorption, respectively, compared with ferrous sulfate. [Zhou J (2025); evidence level 4]
- Iron fortification can help to treat anaemia, but most current fortificants are limited by low absorption and/or poor sensory properties. [Zhou J (2025); evidence level 4]
- Here we introduce oat protein nanofibrils (OatNF) carrying ultrasmall iron nanoparticles that are engineered to carry iron in ferrous or ferric form. [Zhou J (2025); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
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