Quick Answer
Inositol Pms Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention.
Key Takeaways
- 01Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention. [Hatami A (2026)]
- 02Results Compared to placebo, Vitex significantly increased total antioxidant capacity (effect size = 13.01), glutathione peroxidase (3.35), reduced glutathione (3.88), total thiol (3.34), and HDL (5.74) (all p Conclusions Vitex agnus-castus improved oxidative stress markers and insulin resistance and favorably modulated clinical manifestations of PCOS. [Hatami A (2026)]
- 03Objective This randomized controlled trial investigated the efficacy of standardized Vitex agnus-castus extract in managing features of PCOS. [Hatami A (2026)]
- 04The primary aim was to assess changes in oxidative stress markers; secondary outcomes included lipid profile, insulin resistance, and clinical signs such as hirsutism and menstrual frequency. [Hatami A (2026)]
The current Migaku evidence database contains 2 reusable source documents for Inositol Pms Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove.
- Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention. [Hatami A (2026); evidence level 2]
- Results Compared to placebo, Vitex significantly increased total antioxidant capacity (effect size = 13.01), glutathione peroxidase (3.35), reduced glutathione (3.88), total thiol (3.34), and HDL (5.74) (all p Conclusions Vitex agnus-castus improved oxidative stress markers and insulin resistance and favorably modulated clinical manifestations of PCOS. [Hatami A (2026); evidence level 2]
- Objective This randomized controlled trial investigated the efficacy of standardized Vitex agnus-castus extract in managing features of PCOS. [Hatami A (2026); evidence level 2]
- The primary aim was to assess changes in oxidative stress markers; secondary outcomes included lipid profile, insulin resistance, and clinical signs such as hirsutism and menstrual frequency. [Hatami A (2026); evidence level 2]
- While no prior protocol was registered, no quantitative meta-analysis was performed, and a formal risk-of-bias assessment of individual studies was not conducted. [Alsuwaidi Azza (2026); evidence level 3]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources
- The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study.
- Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications