Is Inositol Pms Randomized Trial safe?

Updated July 2026

Quick Answer

Inositol Pms Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention.

Key Takeaways

  • 01Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention. [Hatami A (2026)]
  • 02Results Compared to placebo, Vitex significantly increased total antioxidant capacity (effect size = 13.01), glutathione peroxidase (3.35), reduced glutathione (3.88), total thiol (3.34), and HDL (5.74) (all p Conclusions Vitex agnus-castus improved oxidative stress markers and insulin resistance and favorably modulated clinical manifestations of PCOS. [Hatami A (2026)]
  • 03Objective This randomized controlled trial investigated the efficacy of standardized Vitex agnus-castus extract in managing features of PCOS. [Hatami A (2026)]
  • 04The primary aim was to assess changes in oxidative stress markers; secondary outcomes included lipid profile, insulin resistance, and clinical signs such as hirsutism and menstrual frequency. [Hatami A (2026)]
The current Migaku evidence database contains 2 reusable source documents for Inositol Pms Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Serum total antioxidant capacity, glutathione peroxidase, reduced glutathione, and other biochemical and clinical parameters were assessed preand post-intervention. [Hatami A (2026); evidence level 2] - Results Compared to placebo, Vitex significantly increased total antioxidant capacity (effect size = 13.01), glutathione peroxidase (3.35), reduced glutathione (3.88), total thiol (3.34), and HDL (5.74) (all p Conclusions Vitex agnus-castus improved oxidative stress markers and insulin resistance and favorably modulated clinical manifestations of PCOS. [Hatami A (2026); evidence level 2] - Objective This randomized controlled trial investigated the efficacy of standardized Vitex agnus-castus extract in managing features of PCOS. [Hatami A (2026); evidence level 2] - The primary aim was to assess changes in oxidative stress markers; secondary outcomes included lipid profile, insulin resistance, and clinical signs such as hirsutism and menstrual frequency. [Hatami A (2026); evidence level 2] - While no prior protocol was registered, no quantitative meta-analysis was performed, and a formal risk-of-bias assessment of individual studies was not conducted. [Alsuwaidi Azza (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study.
  2. Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications