What does the evidence say about Holy Basil Anxiety Randomized Trial?

The current Migaku evidence database contains 2 reusable source documents for Holy Basil Anxiety Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Results At day 60, both VL-G-A57 and VL-G-E12 significantly reduced Perceived Stress Scale (PSS) scores compared to placebo (p Conclusion The study concluded that both VL-G-A57 and VL-G-E12 were associated with reductions in stress, fatigue, and anxiety while improving mood and sleep quality. [McKinney E (2026); evidence level 2] - Background Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis. [McKinney E (2026); evidence level 2] - The current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola, holy basil and Schisandra chinensis (VL-G-A57) and a full-spectrum ashwagandha (VL-G-E12), on stress and related symptoms in individuals with high stress. [McKinney E (2026); evidence level 2] - Depression can affect thoughts, mood, and physical health and can be associated with numerous symptoms such as low mood, fatigue, sadness, insomnia, anhedonia, and cognitive impairment symptoms (Li et al.; Schulz and Arora). [Talaei Mahva (2025); evidence level 2] - Anxiety disorders are the most common associated disorders in depressed patients. [Talaei Mahva (2025); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.