Quick Answer
Flaxseed Triglycerides Meta-Analysis has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Results The primary outcome, serum hs-CRP, was significantly reduced in the intervention group compared to controls (MD: -0.98 μg/mL, p = 0.034).
Key Takeaways
- 01Results The primary outcome, serum hs-CRP, was significantly reduced in the intervention group compared to controls (MD: -0.98 μg/mL, p = 0.034). [Aghamohammadzadeh N (2026)]
- 02Exploratory analyses of secondary outcomes suggested additional potential benefits: total antioxidant capacity improved (MD: +0.60 mmol/L, p p 2 , p p = 0.015), fasting insulin (MD: -0.94 μIU/mL, p = 0.008), homeostatic model assessment of insulin resistance (MD: -1.31, p = 0.001), triglycerides (MD: -15.00 mg/dL, p = 0.020), and total cholesterol (MD: -2.52 mg/dL, p = 0.028). [Aghamohammadzadeh N (2026)]
- 03Physical health-related quality of life, including pain scores and physical functioning, also improved significantly ( p Conclusion Cosupplementation with flaxseed oil and high-dose vitamin D 3 significantly reduced systemic inflammation in elderly patients with T2DM. [Aghamohammadzadeh N (2026)]
- 04Aims This study aimed to evaluate the effects of cosupplementation with high-dose vitamin D3 and flaxseed oil on inflammatory markers, oxidative stress, and metabolic health in elderly patients with T2DM. [Aghamohammadzadeh N (2026)]
The current Migaku evidence database contains 2 reusable source documents for Flaxseed Triglycerides Meta-Analysis. This answer focuses on strength of evidence and what the studies can or cannot prove.
- Results The primary outcome, serum hs-CRP, was significantly reduced in the intervention group compared to controls (MD: -0.98 μg/mL, p = 0.034). [Aghamohammadzadeh N (2026); evidence level 2]
- Exploratory analyses of secondary outcomes suggested additional potential benefits: total antioxidant capacity improved (MD: +0.60 mmol/L, p p 2 , p p = 0.015), fasting insulin (MD: -0.94 μIU/mL, p = 0.008), homeostatic model assessment of insulin resistance (MD: -1.31, p = 0.001), triglycerides (MD: -15.00 mg/dL, p = 0.020), and total cholesterol (MD: -2.52 mg/dL, p = 0.028). [Aghamohammadzadeh N (2026); evidence level 2]
- Physical health-related quality of life, including pain scores and physical functioning, also improved significantly ( p Conclusion Cosupplementation with flaxseed oil and high-dose vitamin D 3 significantly reduced systemic inflammation in elderly patients with T2DM. [Aghamohammadzadeh N (2026); evidence level 2]
- Aims This study aimed to evaluate the effects of cosupplementation with high-dose vitamin D3 and flaxseed oil on inflammatory markers, oxidative stress, and metabolic health in elderly patients with T2DM. [Aghamohammadzadeh N (2026); evidence level 2]
- Hyperglycemia is associated with acute and chronic complications, and in both cases, it affects the cardiovascular system, thereby inherently affecting the entire organism, but mainly the eyes, kidneys, and peripheral nerves [,]. [López-Toledo Sabina (2025); evidence level 2]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources
- An 8-Week Triple-Blind, Randomized, Placebo-Controlled Trial Evaluating High-Dose Vitamin D3 and Flaxseed Oil for Inflammation and Metabolic Health in Elderly Patients With Type 2 Diabetes: Implications for Clinical Management.
- Flaxseed Improves Glucose and Lipid Metabolism in Mexican Subjects with Type 2 Diabetes: A Parallel Randomized Clinical Trial