Does Creatine Working Memory Randomized Trial work?

The current Migaku evidence database contains 2 reusable source documents for Creatine Working Memory Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - The proportion of the world’s population over 60 years is projected to double from 12% to 22% by 2050.Aging is known to be associated with various declines in physical and cognitive function. [Marshall Samantha (2026); evidence level 1] - , , , , Previous research has shown that dietary creatine supplementation is associated with a reduction in the effects of aging on muscle and bone in older adults, especially when combined with RT.Although there has been extensive research on creatine’s effects on physical function in both healthy and clinical populations,the impact of creatine on cognition and brain health remains less well established. [Marshall Samantha (2026); evidence level 1] - While there is evidence that creatine crosses the blood–brain barrier via the creatine transporter,most creatine in the body is known to be stored in skeletal muscle, with only approximately 5% stored in the brain. [Marshall Samantha (2026); evidence level 1] - Actively maintaining muscle mass is essential for reducing sarcopenia, frailty, and cognitive decline in older adults. [Marshall Samantha (2026); evidence level 1] - Creatine is naturally found in red meat and seafood, with trace amounts found in some plants [-]. [Muacevic Alexander (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.