Quick Answer
Collagen Joint Pain Meta-Analysis has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Purpose To assess whether diabetes mellitus (type 1 or type 2) increases the risk of developing adhesive capsulitis (frozen shoulder).
Key Takeaways
- 01Purpose To assess whether diabetes mellitus (type 1 or type 2) increases the risk of developing adhesive capsulitis (frozen shoulder). [Hernigou P (2026)]
- 02Study quality and bias risk were assessed, and when enough data were available, a random-effects meta-analysis was performed to estimate the general association between diabetes and the development of frozen shoulder. [Hernigou P (2026)]
- 03Several additional risk factors were noted across studies, including poor glycemic control, obesity, hyperlipidaemia, hypertension, thyroid issues, age between 40 and 65, female gender, smoking, and alcohol use. [Hernigou P (2026)]
- 04Methods A systematic review and meta-analysis were conducted in 2026 using multiple electronic databases. [Hernigou P (2026)]
The current Migaku evidence database contains 4 reusable source documents for Collagen Joint Pain Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation.
- Purpose To assess whether diabetes mellitus (type 1 or type 2) increases the risk of developing adhesive capsulitis (frozen shoulder). [Hernigou P (2026); evidence level 1]
- Study quality and bias risk were assessed, and when enough data were available, a random-effects meta-analysis was performed to estimate the general association between diabetes and the development of frozen shoulder. [Hernigou P (2026); evidence level 1]
- Several additional risk factors were noted across studies, including poor glycemic control, obesity, hyperlipidaemia, hypertension, thyroid issues, age between 40 and 65, female gender, smoking, and alcohol use. [Hernigou P (2026); evidence level 1]
- Methods A systematic review and meta-analysis were conducted in 2026 using multiple electronic databases. [Hernigou P (2026); evidence level 1]
- From 1990 to 2020, the prevalence of OA rose by 132.2% while the age-standardized incidence rate increased from 233.0 to 255.0 per 100,000 worldwide []. [Lee Woojin (2026); evidence level 3]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources
- The diabetic shoulder: association between diabetes mellitus and adhesive capsulitis - a systematic review and meta-analysis.
- Current State of Orthobiologics in Treatment of Knee Osteoarthritis—Future Directions
- Diabetes-Related Metabolic Osteoarthritis: Advanced Glycation–Collagen Axis, Cartilage Stiffening, and Biomaterials-Based Therapeutic Strategies
- Anatomy changes, signalling pathways, and clinical treatment after ankle sprain