What does the evidence say about Aged Garlic Supplementation Endothelial Function Randomized Trial?

Updated October 2026

Quick Answer

Aged Garlic Supplementation Endothelial Function Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: The use of garlic ( Allium sativum ) for treating arterial hypertension has been recognized as effective for several decades.

Key Takeaways

  • 01The use of garlic ( Allium sativum ) for treating arterial hypertension has been recognized as effective for several decades. [Serrano JCE (2023)]
  • 02However, tolerance to treatment is low, and several technological modifications have been developed to improve its tolerability, such as the aging process at controlled temperature and humidity. [Serrano JCE (2023)]
  • 03Aged garlic extract (AGE) is known to have a protective effect against immune system, endothelial function, oxidative stress and inflammation. [Seo DY (2012)]
  • 04We examined the effects of exercise with and without aged garlic extract administration on body weight, lipid profiles, inflammatory cytokines, and oxidative stress marker in high-fat diet (HFD)-induced obese rats. [Seo DY (2012)]
The current Migaku evidence database contains 2 reusable source documents for Aged Garlic Supplementation Endothelial Function Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - The use of garlic ( Allium sativum ) for treating arterial hypertension has been recognized as effective for several decades. [Serrano JCE (2023); evidence level 2] - However, tolerance to treatment is low, and several technological modifications have been developed to improve its tolerability, such as the aging process at controlled temperature and humidity. [Serrano JCE (2023); evidence level 2] - Aged garlic extract (AGE) is known to have a protective effect against immune system, endothelial function, oxidative stress and inflammation. [Seo DY (2012); evidence level 4] - We examined the effects of exercise with and without aged garlic extract administration on body weight, lipid profiles, inflammatory cytokines, and oxidative stress marker in high-fat diet (HFD)-induced obese rats. [Seo DY (2012); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.
  2. Aged garlic extract enhances exercise-mediated improvement of metabolic parameters in high fat diet-induced obese rats.