Mangosteen Skin Health Randomized Trial: What the Evidence Says

Quick Answer

Mangosteen Skin Health Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 2 randomized trial.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Furthermore, the polyphenol and antioxidant contents of snake fruit pulp have been reported to be higher than those found in mango and mangosteen, and comparable to levels observed in kiwifruit. [Intakhiao Suwipa (2026); evidence level 2]
• In the field of nutricosmetics, research has primarily focused on bioactive compounds with the ability to inhibit skin-aging enzymes, as well as those possessing antimicrobial, antioxidant, and anti-inflammatory properties, all of which contribute to improved skin health and protective effects against environmental stressors. [Intakhiao Suwipa (2026); evidence level 2]
• Inter-rater reliability was found to be good to excellent across each of the outcome measures:= 0.92, 0.9, 0.91, 0.95, 0.96 and 0.78 for MADRS, BDRS, HAM-A, YMRS, SAPAS and LIFE-RIFT, respectively. [Dean Olivia M. (2025); evidence level 2]
• There was little evidence of meaningful differences between the treatment conditions (see Supplementary Table). [Dean Olivia M. (2025); evidence level 2]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

There is trial evidence in the current set, but population and intervention details still matter. For mangosteen skin health randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Intakhiao Suwipa (2026). Effects of Snake Fruit–Infused Massage Oil With Traditional Thai Massage on Skin Quality: A Randomized Controlled Trial. DOI: 10.1155/tswj/2446967. PMCID: PMC13057404. PMID: 41947426. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13057404/
• Dean Olivia M. (2025). The efficacy of adjunctive Garcinia mangostana Linn. (mangosteen) pericarp extract for bipolar depression: 24-week randomised controlled trial. DOI: 10.1192/bjp.2025.108. PMCID: PMC12628125. PMID: 40637133. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12628125/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.