Zeaxanthin Visual Performance Randomized Trial Evidence Table

Structured evidence table for Zeaxanthin Visual Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Zeaxanthin Visual Performance Randomized TrialResults Across the 9 RCTs, lutein-containing supplementation significantly improved MPOD (Hedges' g = -0.589, p p = 0.001).1Wang WX (2026)From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialContrast sensitivity and serum lutein concentrations also improved significantly.1Wang WX (2026)From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialConclusion Lutein-based supplementation is associated with measurable structural and functional visual benefits in early-stage AMD.1Wang WX (2026)From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialPurpose To quantify the effects of lutein-containing supplementation on structural and functional visual outcomes in patients with age-related macular degeneration (AMD), with particular focus on disease stage and treatment exposure.1Wang WX (2026)From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialThis systematic review aimed to evaluate randomized controlled trial (RCT) evidence on the effects of carotenoids, anthocyanins, polyunsaturated fatty acids, and combined nutraceutical formulations on refractive outcomes, axial length, macular pigment optical density (MPOD), visual function, and symptoms of visual fatigue.1Martinez-Perez C (2025)Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialEligible studies were RCTs involving individuals with myopia or at risk of myopia, comparing nutritional supplementation with placebo or active controls.1Martinez-Perez C (2025)Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialTwo reviewers independently screened studies, extracted data, and assessed risk of bias using the Cochrane RoB 2 tool.1Martinez-Perez C (2025)Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
Zeaxanthin Visual Performance Randomized TrialBackground/objectives Nutritional supplementation has been proposed as a potential adjunct strategy in myopia prevention and control through antioxidative, anti-inflammatory, and extracellular matrix-regulating mechanisms.1Martinez-Perez C (2025)Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.

Source documents

  1. From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age-Related Macular Degeneration-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  2. Nutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.