topicXylooligosaccharides Gut Microbiome Randomized Trial
claimIn addition, neo-inulin and neo-levan types of fructans with internal glucose residues can also be found [].
evidence level3
citationYoo Suyeon (2024)
sourceThe Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health
topicXylooligosaccharides Gut Microbiome Randomized Trial
claimBenefits of fructans include gastrointestinal relief, increased calcium bioavailability, induction of apoptotic effects on colon cancer tumor cells, reduction of cholesterol and triglycerides, and modulation of the immune system [,,,].
evidence level3
citationYoo Suyeon (2024)
sourceThe Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health
topicXylooligosaccharides Gut Microbiome Randomized Trial
claimInulin’s health benefits include reducing blood lipogenesis and plasma triacylglycerol concentrations, relieving constipation, reducing the risk of gastrointestinal disease, and enhancing the absorption of calcium, magnesium, and iron () [,].
evidence level3
citationYoo Suyeon (2024)
sourceThe Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health
topicXylooligosaccharides Gut Microbiome Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 Firmicutes Bacteroidetes Actinobacteria Proteobacteria The human gut is home to more than 1000 species of microorganisms, forming a complex ecological community called the gut microbiota [].
evidence level3
citationYoo Suyeon (2024)
sourceThe Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health
topicXylooligosaccharides Gut Microbiome Randomized Trial
claimHowever, despite the potential benefits of prebiotics consumption, a concrete index—derived from data-driven, evidence-based approaches—that can quantitatively evaluate the impact of prebiotics on gut microbiome and host health simultaneously has yet to be demonstrated.
evidence level4
citationLee Dong Hyeon (2023)
sourceEvaluating the prebiotic effect of oligosaccharides on gut microbiome wellness using in vitro fecal fermentation
topicXylooligosaccharides Gut Microbiome Randomized Trial
claimThe GMWI mathematical formula considers the relative abundances of 50 microbial species found to be associated with human health; more specifically, by examining 4347 human stool metagenomes from 34 published studies, 7 and 43 microbial species were observed more frequently (prevalent) and less frequently (scarce), respectively, in healthy people compared to patients with a disease.
evidence level4
citationLee Dong Hyeon (2023)
sourceEvaluating the prebiotic effect of oligosaccharides on gut microbiome wellness using in vitro fecal fermentation
topicXylooligosaccharides Gut Microbiome Randomized Trial
claimFor all five prebiotics, the average relative abundances of Actinobacteria, Bacteroidetes, Fusobacteria, and Proteobacteria increased during the 24 h fecal fermentation period, whereas the average relative abundance of Firmicutes largely decreased.
evidence level4
citationLee Dong Hyeon (2023)
sourceEvaluating the prebiotic effect of oligosaccharides on gut microbiome wellness using in vitro fecal fermentation
topicXylooligosaccharides Gut Microbiome Randomized Trial
claim1 2 , 3 4 , 5 6 5 7 8 , 9 10 , 11 12 , Lactobacillus Bifidobacterium Diet alters the composition of the gastrointestinal microbiome, which in turn has an important role in regulating our overall health.
evidence level4
citationLee Dong Hyeon (2023)
sourceEvaluating the prebiotic effect of oligosaccharides on gut microbiome wellness using in vitro fecal fermentation