topicXanthohumol Blood Glucose Randomized Trial
claimSafety and Tolerability of Xanthohumol in Adults With Crohn's Disease: Results of a Triple‐Masked, Randomized, Placebo‐Controlled Phase 2 Trial
evidence level2
citationBradley R (2026)
sourceSafety and Tolerability of Xanthohumol in Adults With Crohn's Disease: Results of a Triple‐Masked, Randomized, Placebo‐Controlled Phase 2 Trial
topicXanthohumol Blood Glucose Randomized Trial
claimC k t t VCO VO 1 2 3 4 5 6 7 8 9 10 Xanthohumol is a prenylated chalcone that can be found at low concentrations in hops, which is why intake of xanthohumol via food is only possible in small quantities [,,].
evidence level2
citationBrehmer‐Henkel Sara (2026)
sourceThe Bioavailability of Xanthohumol in Humans and the Influence of Formulation and Dose: Randomized Controlled Trial Data
topicXanthohumol Blood Glucose Randomized Trial
claimSmaller quantities of mixed metabolites containing sulfates and glucuronides as well as double glucuronide conjugates of xanthohumol and derived prenylated chalcones and flavonoids were also found.
evidence level2
citationBrehmer‐Henkel Sara (2026)
sourceThe Bioavailability of Xanthohumol in Humans and the Influence of Formulation and Dose: Randomized Controlled Trial Data
topicXanthohumol Blood Glucose Randomized Trial
claimBy contrast, reductions of cardiometabolic risk parameters in glucose and lipid metabolism have been demonstrated in animal models [,].
evidence level2
citationBrehmer‐Henkel Sara (2026)
sourceThe Bioavailability of Xanthohumol in Humans and the Influence of Formulation and Dose: Randomized Controlled Trial Data
topicXanthohumol Blood Glucose Randomized Trial
claimIntestinal absorption and consequently the bioavailability of many flavonoids are limited due to their hydrophobic properties [,,].
evidence level2
citationBrehmer‐Henkel Sara (2026)
sourceThe Bioavailability of Xanthohumol in Humans and the Influence of Formulation and Dose: Randomized Controlled Trial Data