topicWalnut Lipid Profile Randomized Trial
claimAlthough several clinical trials have examined their impact on the lipid profile, results have been inconsistent, and evidence regarding their effects on apolipoproteins is limited.
evidence level1
citationMashayekhi G (2026)
sourceEffects of Walnut Consumption on Blood Lipid Profile and Apolipoproteins in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of 49 Randomized Controlled Trials.
topicWalnut Lipid Profile Randomized Trial
claimThe pooled analysis of 49 RCTs (57 effect sizes; 4611 participants) showed that Walnut consumption significantly reduced and TG (WMD: -6.24 mg/dL, 95% CI: [-9.49, -2.99], p p p p = 0.145), Apo-A1 (WMD: 0.0, 95% CI: [-0.01, 0.00], p = 0.573), or Apo-B (WMD: 0.1, 95% CI: [-0.02, 0.05], p = 0.462).
evidence level1
citationMashayekhi G (2026)
sourceEffects of Walnut Consumption on Blood Lipid Profile and Apolipoproteins in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of 49 Randomized Controlled Trials.
topicWalnut Lipid Profile Randomized Trial
claimIn conclusion, walnut supplementation improves the lipid profile by significantly lowering TC, LDL-C, and TG levels.
evidence level1
citationMashayekhi G (2026)
sourceEffects of Walnut Consumption on Blood Lipid Profile and Apolipoproteins in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of 49 Randomized Controlled Trials.
topicWalnut Lipid Profile Randomized Trial
claimWalnuts ( Juglans regia L.) are rich in polyunsaturated fatty acids (PUFAs), fiber, and bioactive compounds that may positively affect lipid metabolism.
evidence level1
citationMashayekhi G (2026)
sourceEffects of Walnut Consumption on Blood Lipid Profile and Apolipoproteins in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of 49 Randomized Controlled Trials.