Structured evidence table for Walnut Cardiometabolic Wellness Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Walnut Cardiometabolic Wellness Randomized Trial | Importantly, urolithin metabotypes have been associated with host characteristics such as aging and cardiometabolic status, underscoring that exposure to bioactive urolithins depends not only on precursor intake but also on microbiome configuration (,). | 3 | Hu Lingmin (2026) | Urolithins in clinical translation: from gut microbial metabolites to precision interventions |
| Walnut Cardiometabolic Wellness Randomized Trial | This promise has begun to extend into humans: a first-in-human study demonstrated favorable safety, bioavailability, and molecular signatures consistent with improved mitochondrial and cellular health, while a subsequent randomized clinical trial in older adults reported improved muscle endurance and favorable changes in plasma biomarkers despite neutral findings for some primary functional endpoints (,). | 3 | Hu Lingmin (2026) | Urolithins in clinical translation: from gut microbial metabolites to precision interventions |
| Walnut Cardiometabolic Wellness Randomized Trial | We then discuss the mechanistic basis of urolithin action, with emphasis on pathways most likely to be relevant, and critically evaluate evidence across major disease contexts by integrating pre-clinical findings with available human data. | 3 | Hu Lingmin (2026) | Urolithins in clinical translation: from gut microbial metabolites to precision interventions |
| Walnut Cardiometabolic Wellness Randomized Trial | 1 2 2 3 5 3 4 5 6 7 8 6 9 Gordonibacter urolithinfaciens Gordonibacter pamelaeae Urolithins are dibenzopyran-6-one derivatives generated through the gut microbial metabolism of ellagitannins and ellagic acid, polyphenols abundant in pomegranate, walnuts, and several berries. | 3 | Hu Lingmin (2026) | Urolithins in clinical translation: from gut microbial metabolites to precision interventions |
| Walnut Cardiometabolic Wellness Randomized Trial | Continuous glucose monitoring (CGM)-derived metrics (average glucose [AG], glycemia risk index [GRI], time in range [TIR] 70-180 mg/dL, TITR, coefficient of variation [CV]) were evaluated via static pre-post comparison. | 4 | Firmansyah BS (2026) | Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally Delivered Metabolic Wellness Program. |
| Walnut Cardiometabolic Wellness Randomized Trial | The low TITR ( P P P r = 0.31, P Conclusions While static CGM metrics remained unchanged, MWP participation was associated with significant behavioral and temporal glycemic improvements, particularly among those with lower baseline TITR. | 4 | Firmansyah BS (2026) | Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally Delivered Metabolic Wellness Program. |
| Walnut Cardiometabolic Wellness Randomized Trial | Background Health care workers face elevated cardiometabolic risks due to irregular hours and chronic stress, yet targeted interventions are limited. | 4 | Firmansyah BS (2026) | Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally Delivered Metabolic Wellness Program. |
| Walnut Cardiometabolic Wellness Randomized Trial | This study evaluated an 8-week digital Metabolic Wellness Program (MWP), combining lifestyle education with real-time continuous glucose monitoring (CGM). | 4 | Firmansyah BS (2026) | Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally Delivered Metabolic Wellness Program. |
Source documents