exercise performance

Ubiquinol Exercise Performance Randomized Trial Evidence Table

Structured evidence table for Ubiquinol Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Ubiquinol Exercise Performance Randomized TrialThe results demonstrated that oral coenzyme Q10 elevated blood coenzyme Q10 concentration (standardized mean difference: 2.710, 95% confidence interval: 1.57-3.85, p < 0.00001) and reduced blood malondialdehyde concentration (standardized mean difference: -0.289, 95% confidence interval: -0.541 to -0.038, p = 0.024).1Zhang Y (2026)Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
Ubiquinol Exercise Performance Randomized TrialAdditionally, oral coenzyme Q10 was found to reduce blood creatine kinase values (standardized mean difference: -1.532, 95% confidence interval: -2.856 to -0.209, p = 0.023), suggesting a potential protective effect on skeletal muscle.1Zhang Y (2026)Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
Ubiquinol Exercise Performance Randomized TrialQuantitative and qualitative analyses were performed.ResultsThe study screened 14 randomized controlled trials that included a total of 433 subjects.1Zhang Y (2026)Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
Ubiquinol Exercise Performance Randomized TrialThe reduced form of CoQ 10 , ubiquinol (UQH 2 ), has greater bioavailability than ubiquinone, but the effects of UQH 2 supplementation on mitochondrial respiratory function and exercise capacity are unclear.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Ubiquinol Exercise Performance Randomized TrialCompared to pre-supplementation and PLA, UQH 2 supplementation increased plasma [CoQ 10 ] (P 2 : 0.073 ± 0.039 vs.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Ubiquinol Exercise Performance Randomized TrialSix-weeks UQH 2 supplementation increased plasma [CoQ 10 ] and oxidative phosphorylation coupling efficiency, but did not alter mitochondrial leak proteins, T Lim or V̇O 2 kinetics during severe-intensity exercise in healthy, active males.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
Ubiquinol Exercise Performance Randomized TrialCoenzyme Q10 (CoQ 10 ) is an integral component of the mitochondrial electron transfer system.4Acton JP (2026)Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicUbiquinol Exercise Performance Randomized Trial
claimThe results demonstrated that oral coenzyme Q10 elevated blood coenzyme Q10 concentration (standardized mean difference: 2.710, 95% confidence interval: 1.57-3.85, p < 0.00001) and reduced blood malondialdehyde concentration (standardized mean difference: -0.289, 95% confidence interval: -0.541 to -0.038, p = 0.024).
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicUbiquinol Exercise Performance Randomized Trial
claimAdditionally, oral coenzyme Q10 was found to reduce blood creatine kinase values (standardized mean difference: -1.532, 95% confidence interval: -2.856 to -0.209, p = 0.023), suggesting a potential protective effect on skeletal muscle.
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicUbiquinol Exercise Performance Randomized Trial
claimQuantitative and qualitative analyses were performed.ResultsThe study screened 14 randomized controlled trials that included a total of 433 subjects.
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicUbiquinol Exercise Performance Randomized Trial
claimThe reduced form of CoQ 10 , ubiquinol (UQH 2 ), has greater bioavailability than ubiquinone, but the effects of UQH 2 supplementation on mitochondrial respiratory function and exercise capacity are unclear.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicUbiquinol Exercise Performance Randomized Trial
claimCompared to pre-supplementation and PLA, UQH 2 supplementation increased plasma [CoQ 10 ] (P 2 : 0.073 ± 0.039 vs.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicUbiquinol Exercise Performance Randomized Trial
claimSix-weeks UQH 2 supplementation increased plasma [CoQ 10 ] and oxidative phosphorylation coupling efficiency, but did not alter mitochondrial leak proteins, T Lim or V̇O 2 kinetics during severe-intensity exercise in healthy, active males.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.
topicUbiquinol Exercise Performance Randomized Trial
claimCoenzyme Q10 (CoQ 10 ) is an integral component of the mitochondrial electron transfer system.
evidence level4
citationActon JP (2026)
sourceEffect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.

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Source documents

  1. Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
  2. Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.