topicTocotrienols Skin Hydration Randomized Trial
claimResults According to the repeated-measures ANOVA, the control and study group had a significant reduction in follicular papule counts over time (all p Conclusion The combined formula effectively reduced follicular papules, improved skin hydration, decreased TEWL, and alleviated depressive symptoms in KP patients.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicTocotrienols Skin Hydration Randomized Trial
claimObjective Keratosis pilaris (KP) is a common follicular keratotic skin disorder characterized by follicular papules and skin roughness, often accompanied by itching and inflammation, significantly affecting appearance and psychological health.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicTocotrienols Skin Hydration Randomized Trial
claimMethods This 28-day prospective, open-label, randomized controlled study evaluated the effectiveness of a novel combined formula for KP treatment.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicTocotrienols Skin Hydration Randomized Trial
claimThis research aims to investigate the efficacy of tocotrienol-rich fraction (TRF) on various health parameters associated with general well-being in individuals aged between 50 years and 75 years.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienols Skin Hydration Randomized Trial
claimBackground Tocotrienol, a naturally occurring form of vitamin E, has been extensively studied for its potent antioxidant, anti-inflammatory, and immune-stimulating properties.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienols Skin Hydration Randomized Trial
claimHowever, the clinical impact of tocotrienol supplementation on older adults' overall health and well-being remains relatively unexplored.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.