topicTocotrienols Blood Lipids Randomized Trial
claimThis research aims to investigate the efficacy of tocotrienol-rich fraction (TRF) on various health parameters associated with general well-being in individuals aged between 50 years and 75 years.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienols Blood Lipids Randomized Trial
claimBackground Tocotrienol, a naturally occurring form of vitamin E, has been extensively studied for its potent antioxidant, anti-inflammatory, and immune-stimulating properties.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienols Blood Lipids Randomized Trial
claimHowever, the clinical impact of tocotrienol supplementation on older adults' overall health and well-being remains relatively unexplored.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienols Blood Lipids Randomized Trial
claimMoreover, changes in blood markers associated with inflammation, oxidative stress, and neurotropic activity were examined.
evidence level2
citationLopresti AL (2025)
sourceAn examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial.
topicTocotrienols Blood Lipids Randomized Trial
claimResults Compared to the placebo, tocotrienol supplementation was associated with greater improvements in general memory ( p = 0.045, 95% CI: 0.34, 32.21).
evidence level2
citationLopresti AL (2025)
sourceAn examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial.
topicTocotrienols Blood Lipids Randomized Trial
claimConclusion This is the first controlled study demonstrating the cognitive-enhancing and sleep-promoting effects of stand-alone supplementation with tocotrienols.
evidence level2
citationLopresti AL (2025)
sourceAn examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial.
topicTocotrienols Blood Lipids Randomized Trial
claimBackground/objectives Tocotrienols are a form of vitamin E that may have neuroprotective effects.
evidence level2
citationLopresti AL (2025)
sourceAn examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial.