topicTocotrienol Skin Aging Randomized Trial
claimThis research aims to investigate the efficacy of tocotrienol-rich fraction (TRF) on various health parameters associated with general well-being in individuals aged between 50 years and 75 years.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienol Skin Aging Randomized Trial
claimBackground Tocotrienol, a naturally occurring form of vitamin E, has been extensively studied for its potent antioxidant, anti-inflammatory, and immune-stimulating properties.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienol Skin Aging Randomized Trial
claimHowever, the clinical impact of tocotrienol supplementation on older adults' overall health and well-being remains relatively unexplored.
evidence level2
citationAmir Razak NAN (2025)
sourceEffectiveness of Tocotrienol-Rich Fraction in Older Adults: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial.
topicTocotrienol Skin Aging Randomized Trial
claimCollagen, along with antioxidants such as curcumin and glutathione, have gained increased utilization/awareness in recent years, providing dermal health benefits especially in women who experience declining or loss of estrogen with aging.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicTocotrienol Skin Aging Randomized Trial
claimThe evidence of oral collagen as a nutraceutical is robust for improving several aspects of dermal health.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicTocotrienol Skin Aging Randomized Trial
claimFor example, the epidermis is without a blood supply and does not have the same circulation and nutrient delivery found in the dermis [–].
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicTocotrienol Skin Aging Randomized Trial
claimThe present narrative review is an extension of a larger project that covered polyphenols and phytoestrogens.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review