topicTaurine Exercise Performance Randomized Trial
claimAs life expectancy increases, age-associated declines in muscle strength, metabolic flexibility, immune responsiveness, and cognitive resilience have become major contributors to morbidity and diminished quality of life.
evidence level3
citationChen Zhigang (2026)
sourceTaurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
topicTaurine Exercise Performance Randomized Trial
claimDespite these benefits, the biological response to exercise is often dampened in aging due to reduced mitochondrial efficiency, lower anabolic sensitivity, impaired antioxidant capacity, and chronic inflammatory signaling.
evidence level3
citationChen Zhigang (2026)
sourceTaurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
topicTaurine Exercise Performance Randomized Trial
claimAs a result, older adults commonly experience delayed recovery, attenuated gains in muscle strength or aerobic capacity, and limited adaptations compared with younger individuals.
evidence level3
citationChen Zhigang (2026)
sourceTaurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
topicTaurine Exercise Performance Randomized Trial
claimKirkwood, 2005 Lutz and Quinn, 2012 Falahi et al., 2025 Liang et al., 2022 Hébert, 1997 The steady growth of the global older population has intensified scientific attention toward biological processes that erode functional capacity and compromise independence with aging.
evidence level3
citationChen Zhigang (2026)
sourceTaurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways
topicTaurine Exercise Performance Randomized Trial
claimAlthough clinical evidence remains somewhat sparse, it suggests that taurine supplementation may augment exercise capacity, improve glycemic control, and enhance cardiac function in populations afflicted with metabolic syndrome, diabetes, and heart failure (,).
evidence level3
citationZhang LiMing (2026)
sourceBeyond weight loss, cognitive health, and glycemic control: taurine supplementation as a reprogrammer of adipose tissue plasticity, physical performance, metabolic flexibility, neuroinflammaging, and cardiac remodeling in obesity, aging, and diabetes
topicTaurine Exercise Performance Randomized Trial
claimEmpirical evidence indicates that the synergistic application of aerobic and resistance training can alleviate diabetes-induced myocardial apoptosis, promote neurotrophic factor expression, and enhance glycemic regulation in preclinical models ().
evidence level3
citationZhang LiMing (2026)
sourceBeyond weight loss, cognitive health, and glycemic control: taurine supplementation as a reprogrammer of adipose tissue plasticity, physical performance, metabolic flexibility, neuroinflammaging, and cardiac remodeling in obesity, aging, and diabetes
topicTaurine Exercise Performance Randomized Trial
claimBy amalgamating evidence from diverse tissues, experimental models, and varying patient cohorts, this review offers a comprehensive framework for comprehending taurine and exercise as complementary modalities, thus providing pragmatic implications for metabolic, cardiovascular, and neuroprotective strategies.
evidence level3
citationZhang LiMing (2026)
sourceBeyond weight loss, cognitive health, and glycemic control: taurine supplementation as a reprogrammer of adipose tissue plasticity, physical performance, metabolic flexibility, neuroinflammaging, and cardiac remodeling in obesity, aging, and diabetes
topicTaurine Exercise Performance Randomized Trial
claim1 2 3 4 Obesity, senescence, and diabetes represent a triadic constellation of health challenges that are increasingly prevalent and interrelated, imposing significant metabolic, cardiovascular, and neurological burdens on a global scale.
evidence level3
citationZhang LiMing (2026)
sourceBeyond weight loss, cognitive health, and glycemic control: taurine supplementation as a reprogrammer of adipose tissue plasticity, physical performance, metabolic flexibility, neuroinflammaging, and cardiac remodeling in obesity, aging, and diabetes