Structured evidence table for Synbiotic Supplementation Gut Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Synbiotic Supplementation Gut Health Randomized Trial | Hens in the late laying cycle commonly experience age-associated physiological and structural constraints that can alter production efficiency, egg integrity, and welfare (;). | 4 | Pongmanee Koonphol (2026) | Influence of synbiotic supplementation on performance, fecal consistency, cecal microbiome, and egg quality of hens during late laying phase |
| Synbiotic Supplementation Gut Health Randomized Trial | Attia et al., 2020 Liu et al., 2023 Although egg size typically increases with age, the functional capacity of the shell gland does not expand proportionally, often resulting in a reduced shell-to-egg surface area coverage and a progressive decline in eggshell material accretion (;). | 4 | Pongmanee Koonphol (2026) | Influence of synbiotic supplementation on performance, fecal consistency, cecal microbiome, and egg quality of hens during late laying phase |
| Synbiotic Supplementation Gut Health Randomized Trial | While several studies have reported improved gut microbiota balance, egg production, and egg quality with synbiotic supplementation (;;;), findings remain inconsistent, likely due to differences in synbiotic composition, microbial strains, dosage, and the age of birds. | 4 | Pongmanee Koonphol (2026) | Influence of synbiotic supplementation on performance, fecal consistency, cecal microbiome, and egg quality of hens during late laying phase |
| Synbiotic Supplementation Gut Health Randomized Trial | Guyonnet, 2023 Liu et al., 2023 Wang et al., 2019 The global demand for poultry products, particularly eggs, continues to rise as they serve as an affordable and high-quality source of animal protein (). | 4 | Pongmanee Koonphol (2026) | Influence of synbiotic supplementation on performance, fecal consistency, cecal microbiome, and egg quality of hens during late laying phase |
| Synbiotic Supplementation Gut Health Randomized Trial | This study evaluated the immune response and early protective effects of a synbiotic in broiler chickens using a reduced in vivo model of Salmonella Typhimurium infection. | 4 | Rivera Pérez W (2026) | Protective Effect of Synbiotic Supplementation Against <i>Salmonella</i> Typhimurium Infection in Young Broiler Chickens. |
| Synbiotic Supplementation Gut Health Randomized Trial | Synbiotic supplementation reduced bacterial colonization and adhesion in the ileum, as assessed by intestinal content isolation and immunofluorescence analysis. | 4 | Rivera Pérez W (2026) | Protective Effect of Synbiotic Supplementation Against <i>Salmonella</i> Typhimurium Infection in Young Broiler Chickens. |
| Synbiotic Supplementation Gut Health Randomized Trial | Additionally, the synbiotics mitigated lesion severity in the intestine, liver, and heart, increased anti-inflammatory IL-10 expression, and reduced pro-inflammatory cytokines IL-1β and TNF-α. | 4 | Rivera Pérez W (2026) | Protective Effect of Synbiotic Supplementation Against <i>Salmonella</i> Typhimurium Infection in Young Broiler Chickens. |
| Synbiotic Supplementation Gut Health Randomized Trial | Salmonella infection in poultry remains a major concern due to its economic impact and public health risks. | 4 | Rivera Pérez W (2026) | Protective Effect of Synbiotic Supplementation Against <i>Salmonella</i> Typhimurium Infection in Young Broiler Chickens. |
Source documents