Structured evidence table for Synbiotic Constipation Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Synbiotic Constipation Randomized Trial | Synbiotic supplementation significantly reduced levels of key muscle injury markers (CK, p < 0.001; AST, p = 0.01) and inflammatory markers (TNF-α, p < 0.001; hs-CRP, p < 0.001) compared to placebo. | 2 | Bideshki MV (2026) | Synbiotic supplementation effects on muscle damage and inflammation in professional futsal players in a randomized clinical trial. |
| Synbiotic Constipation Randomized Trial | It also significantly improved body composition by reducing fat mass and body fat percentage (both p = 0.01). | 2 | Bideshki MV (2026) | Synbiotic supplementation effects on muscle damage and inflammation in professional futsal players in a randomized clinical trial. |
| Synbiotic Constipation Randomized Trial | Professional futsal players experience significant muscle injury, inflammation, and body composition alterations due to intense training. | 2 | Bideshki MV (2026) | Synbiotic supplementation effects on muscle damage and inflammation in professional futsal players in a randomized clinical trial. |
| Synbiotic Constipation Randomized Trial | This 12-week double-blind, randomized clinical trial investigated the efficacy of synbiotic supplementation in 25 players assigned to either a synbiotic group (n = 13) receiving 10⁹ CFU of seven probiotic strains plus 375 mg fructooligosaccharides, or a placebo group (n = 12). | 2 | Bideshki MV (2026) | Synbiotic supplementation effects on muscle damage and inflammation in professional futsal players in a randomized clinical trial. |
| Synbiotic Constipation Randomized Trial | Probiotics can alleviate some gastrointestinal (GI) symptoms; however, evidence for their impact on bloating, gas and abdominal discomfort in otherwise healthy populations remains limited. | 2 | Allegretti JR (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort. |
| Synbiotic Constipation Randomized Trial | Mechanistic studies suggest that synbiotics may influence the underlying mechanisms of bloating, including increased gas production, impaired gut motility, and visceral hypersensitivity, but there is a paucity of data from large trials evaluating clinical outcomes. | 2 | Allegretti JR (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort. |
| Synbiotic Constipation Randomized Trial | Results : The multi-species synbiotic improved GI quality-of-life compared to placebo (0.80 vs. | 2 | Allegretti JR (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort. |
| Synbiotic Constipation Randomized Trial | Background: Bloating, gas, and abdominal discomfort are common in healthy individuals but lack effective interventions. | 2 | Allegretti JR (2026) | A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort. |
Source documents