topicSpirulina Immune Support Randomized Trial
claimChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Immune Support Randomized Trial
claimWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Immune Support Randomized Trial
claim2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Immune Support Randomized Trial
claimChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Immune Support Randomized Trial
claimThis review summarizes current evidence on nutritional compounds that target aging-related pathways, focusing on interventions that influence mitochondrial health, cognitive performance, immune function, metabolic regulation, and maintenance of muscle mass in older adults.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicSpirulina Immune Support Randomized Trial
claimRecent findings Evidence indicates that several targeted nutrients, including protein, probiotics, antioxidants, and emerging mitochondrial-support compounds, may contribute to healthy aging.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicSpirulina Immune Support Randomized Trial
claimA personalized, evidence-informed supplementation strategy integrated with exercise and balanced nutrition may help optimize physiological function in aging adults.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicSpirulina Immune Support Randomized Trial
claimPurpose of review Aging is marked by progressive physiological decline driven by chronic inflammation, mitochondrial dysfunction, and impaired metabolic and musculoskeletal resilience.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.