Silicon Supplementation Hair Nails Randomized Trial Evidence Table

Structured evidence table for Silicon Supplementation Hair Nails Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Silicon Supplementation Hair Nails Randomized TrialThis has led to an increased dermatological interest in biotin supplementation for improving hair strength, reducing brittleness, and enhancing skin health [].2Muacevic Alexander (2025)The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Silicon Supplementation Hair Nails Randomized TrialHowever, there is limited scientific evidence assessing the safety and efficacy of these combinations in controlled human studies [,].2Muacevic Alexander (2025)The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Silicon Supplementation Hair Nails Randomized TrialThe evaluations aim to validate the therapeutic potential of these formulations, supporting evidence-based applications for improving hair and skin health.2Muacevic Alexander (2025)The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Silicon Supplementation Hair Nails Randomized Trial1 2 3 4 Biotin, a water-soluble B-complex vitamin, is essential for maintaining healthy hair and skin due to its pivotal role in cellular metabolism [].2Muacevic Alexander (2025)The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Silicon Supplementation Hair Nails Randomized TrialDietary supplementation with 0.2%, 0.4%, and 0.8% silica significantly increased serum levels of IL-2 and IL-4 ( p p p p 2 significantly increased serum concentrations of β-endorphin, estradiol, growth hormone, luteinizing hormone, and progesterone ( p p p 2 supplementation significantly altered serum Cu and Zn levels ( p p > 0.05).4Chen Y (2026)Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
Silicon Supplementation Hair Nails Randomized TrialIn conclusion, dietary supplementation with 0.2-0.4% SiO 2 effectively improves egg production rate, along with enhancing immune function, modulating reproductive hormone secretion, and regulating serum Cu/Zn homeostasis in late-phase laying hens.4Chen Y (2026)Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
Silicon Supplementation Hair Nails Randomized TrialSilicon (Si) is an essential trace element involved in multiple physiological processes of animals.4Chen Y (2026)Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
Silicon Supplementation Hair Nails Randomized TrialThis study aimed to investigate the dose-dependent effects of dietary silica (SiO 2 ) supplementation on production performance and key blood parameters in laying hens.4Chen Y (2026)Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimThis has led to an increased dermatological interest in biotin supplementation for improving hair strength, reducing brittleness, and enhancing skin health [].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimHowever, there is limited scientific evidence assessing the safety and efficacy of these combinations in controlled human studies [,].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimThe evaluations aim to validate the therapeutic potential of these formulations, supporting evidence-based applications for improving hair and skin health.
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claim1 2 3 4 Biotin, a water-soluble B-complex vitamin, is essential for maintaining healthy hair and skin due to its pivotal role in cellular metabolism [].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimDietary supplementation with 0.2%, 0.4%, and 0.8% silica significantly increased serum levels of IL-2 and IL-4 ( p p p p 2 significantly increased serum concentrations of β-endorphin, estradiol, growth hormone, luteinizing hormone, and progesterone ( p p p 2 supplementation significantly altered serum Cu and Zn levels ( p p > 0.05).
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimIn conclusion, dietary supplementation with 0.2-0.4% SiO 2 effectively improves egg production rate, along with enhancing immune function, modulating reproductive hormone secretion, and regulating serum Cu/Zn homeostasis in late-phase laying hens.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimSilicon (Si) is an essential trace element involved in multiple physiological processes of animals.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimThis study aimed to investigate the dose-dependent effects of dietary silica (SiO 2 ) supplementation on production performance and key blood parameters in laying hens.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.

Source documents

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
  2. Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.