topicSilicon Supplementation Hair Nails Randomized Trial
claimThis has led to an increased dermatological interest in biotin supplementation for improving hair strength, reducing brittleness, and enhancing skin health [].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimHowever, there is limited scientific evidence assessing the safety and efficacy of these combinations in controlled human studies [,].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimThe evaluations aim to validate the therapeutic potential of these formulations, supporting evidence-based applications for improving hair and skin health.
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claim1 2 3 4 Biotin, a water-soluble B-complex vitamin, is essential for maintaining healthy hair and skin due to its pivotal role in cellular metabolism [].
evidence level2
citationMuacevic Alexander (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
topicSilicon Supplementation Hair Nails Randomized Trial
claimDietary supplementation with 0.2%, 0.4%, and 0.8% silica significantly increased serum levels of IL-2 and IL-4 ( p p p p 2 significantly increased serum concentrations of β-endorphin, estradiol, growth hormone, luteinizing hormone, and progesterone ( p p p 2 supplementation significantly altered serum Cu and Zn levels ( p p > 0.05).
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimIn conclusion, dietary supplementation with 0.2-0.4% SiO 2 effectively improves egg production rate, along with enhancing immune function, modulating reproductive hormone secretion, and regulating serum Cu/Zn homeostasis in late-phase laying hens.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimSilicon (Si) is an essential trace element involved in multiple physiological processes of animals.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.
topicSilicon Supplementation Hair Nails Randomized Trial
claimThis study aimed to investigate the dose-dependent effects of dietary silica (SiO 2 ) supplementation on production performance and key blood parameters in laying hens.
evidence level4
citationChen Y (2026)
sourceDietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation.