Structured evidence table for Silicon Supplementation Bone Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Silicon Supplementation Bone Health Randomized Trial | OVCFs are associated with significant reductions in health-related quality of life, progressive spinal deformity, and increased mortality risk [,]. | 4 | Gazzeri Roberto (2026) | Oral Food Supplement with Bio-Activated Silicium and Vitamins D3 and K2 in the Conservative Management of Osteoporotic Vertebral Compression Fractures |
| Silicon Supplementation Bone Health Randomized Trial | Moreover, OVCFs substantially increase the risk of subsequent vertebral fractures by up to fivefold, initiating a cascade of skeletal fragility that further worsens long-term prognosis [,]. | 4 | Gazzeri Roberto (2026) | Oral Food Supplement with Bio-Activated Silicium and Vitamins D3 and K2 in the Conservative Management of Osteoporotic Vertebral Compression Fractures |
| Silicon Supplementation Bone Health Randomized Trial | 7 8 9 10 11 12 13 14 15 Most OVCFs are initially managed conservatively, and current international guidelines recommend non-operative treatment for stable fractures without neurological compromise [,,]. | 4 | Gazzeri Roberto (2026) | Oral Food Supplement with Bio-Activated Silicium and Vitamins D3 and K2 in the Conservative Management of Osteoporotic Vertebral Compression Fractures |
| Silicon Supplementation Bone Health Randomized Trial | 1 2 3 4 5 6 Osteoporotic vertebral compression fractures (OVCFs) are the most common manifestation of osteoporotic skeletal disease and represent a major global public health burden []. | 4 | Gazzeri Roberto (2026) | Oral Food Supplement with Bio-Activated Silicium and Vitamins D3 and K2 in the Conservative Management of Osteoporotic Vertebral Compression Fractures |
| Silicon Supplementation Bone Health Randomized Trial | Dietary silica intake enhances bone health by promoting calcium absorption and deposition, leading to increased bone mineral density and aiding in the prevention of osteoporosis []. | 4 | Chen Yong (2026) | Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation |
| Silicon Supplementation Bone Health Randomized Trial | The physiological importance of silicon is also verified in human studies, where reduced silicon levels in the aorta are associated with atherosclerosis in the elderly, a condition linked to lipid infiltration in connective tissues and alterations of elastic fibers and the extracellular matrix []. | 4 | Chen Yong (2026) | Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation |
| Silicon Supplementation Bone Health Randomized Trial | (2001) found that dietary supplementation with 2% bentonite significantly improved the growth performance of broilers, with the treatment group showing a 12.3% increase in average daily gain (ADG) and an 8.7% decrease in feed conversion ratio (FCR) compared with the control group []. | 4 | Chen Yong (2026) | Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation |
| Silicon Supplementation Bone Health Randomized Trial | 1 2 3 4 5 6 7 8 9 10 11 Silicon, the second most abundant element in the Earth’s crust, plays a significant role in animal physiology []. | 4 | Chen Yong (2026) | Dietary Silicon Supplementation Improves Egg Production Performance in Late-Phase Laying Hens: Roles of Antioxidant Capacity, Reproductive Hormones, and Serum Cu/Zn Regulation |
Source documents