Structured evidence table for Silicon Skin Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Silicon Skin Hydration Randomized Trial | Skin aging, a multifactorial process influenced by both intrinsic and extrinsic factors, manifests as wrinkles, dryness, reduced elasticity, and altered pore structure. | 2 | Lee E (2025) | Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. |
| Silicon Skin Hydration Randomized Trial | Despite the promising anti-aging effects of low-molecular-weight collagen peptides (LMWCPs), heterogeneity in clinical trial designs poses limitations in fully elucidating their comprehensive efficacy. | 2 | Lee E (2025) | Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. |
| Silicon Skin Hydration Randomized Trial | When SC integrity is compromised, by reduced epidermal lipids or NMF (as in NMF‐deficient xerotic skin) [], intrinsic aging changes in keratinization and lipid production [], or environmental insults, TEWL increases and water‐holding capacity falls []. | 4 | Maletin Nemanja (2026) | Evaluation of a 10% Urea Lotion for Xerosis: Clinical and Patient‐Reported Outcomes From a Prospective Study |
| Silicon Skin Hydration Randomized Trial | In older skin, altered keratinocyte maturation and reduced SC lipid content exacerbate these effects []. | 4 | Maletin Nemanja (2026) | Evaluation of a 10% Urea Lotion for Xerosis: Clinical and Patient‐Reported Outcomes From a Prospective Study |
| Silicon Skin Hydration Randomized Trial | The result is the characteristic dry, rough, and often fissured skin of xerosis. | 4 | Maletin Nemanja (2026) | Evaluation of a 10% Urea Lotion for Xerosis: Clinical and Patient‐Reported Outcomes From a Prospective Study |
| Silicon Skin Hydration Randomized Trial | 1 1 2 3 4 Dry skin (xerosis cutis) is characterized by a deficiency of stratum corneum lipids and natural moisturizing factors (NMF) [], leading to impaired barrier function. | 4 | Maletin Nemanja (2026) | Evaluation of a 10% Urea Lotion for Xerosis: Clinical and Patient‐Reported Outcomes From a Prospective Study |
Source documents