topicSilicon Skin Hair Nails Randomized Trial
claimBackground Biotin, a vital cofactor for carboxylase enzymes, plays a key role in metabolic processes, while silica is believed to support collagen synthesis, contributing to improved skin and hair health.
evidence level2
citationPatel MN (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
topicSilicon Skin Hair Nails Randomized Trial
claimResults In the post-90-day evaluation, hair fall reduced to 20.61 ± 14.39 (p < 0.001) in biotin and 15.71 ± 10.8 (p < 0.001) in biotin with silica.
evidence level2
citationPatel MN (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
topicSilicon Skin Hair Nails Randomized Trial
claimHair growth rate increased by 0.55 mm/day (p < 0.0001) in biotin and 0.57 mm/day (p < 0.0001) in biotin with silica.
evidence level2
citationPatel MN (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
topicSilicon Skin Hair Nails Randomized Trial
claimThis study investigates the dermatological benefits of standardized plant-based supplements formulated with biotin derived from Sesbania grandiflora and a biotin-silica blend extracted from Bambusa arundinacea.
evidence level2
citationPatel MN (2025)
sourceThe Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
topicSilicon Skin Hair Nails Randomized Trial
claimWith increasing consumer and clinical interest, collagen supplementation has expanded rapidly, yet scientific evidence supporting its efficacy in anti-aging and regenerative applications remains inconsistent.
evidence level4
citationIvaskiene T (2025)
sourceCollagen supplementation and regenerative health: advances in biomarker detection and smart material integration.
topicSilicon Skin Hair Nails Randomized Trial
claimThis review critically evaluates current evidence on oral collagen supplementation, integrating insights from over 60 clinical studies assessing its effects on skin aging, musculoskeletal health, and hair disorders.
evidence level4
citationIvaskiene T (2025)
sourceCollagen supplementation and regenerative health: advances in biomarker detection and smart material integration.
topicSilicon Skin Hair Nails Randomized Trial
claimCollagen, the most abundant structural protein in the human body, plays a key role in skin integrity, tissue repair, and extracellular matrix organization.
evidence level4
citationIvaskiene T (2025)
sourceCollagen supplementation and regenerative health: advances in biomarker detection and smart material integration.