Silica Skin Randomized Trial Evidence Table

Structured evidence table for Silica Skin Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Silica Skin Randomized TrialPrevious studies have demonstrated the successful loading and sustained release of bioactive molecules such as omega-3 fatty acids and vitamin D, with improved bioavailability attributed to mucoadhesion and controlled release mechanisms [].2Murad Mariam (2026)Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
Silica Skin Randomized TrialThis significantly reduces the risk of immunogenicity and has been supported by recent studies demonstrating minimal IgE reactivity and the good biocompatibility of sporopollenin-derived materials [,].2Murad Mariam (2026)Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
Silica Skin Randomized TrialCombustion elemental analysis found carbon: 67.9%; hydrogen: 79.19%; and nitrogen: 0.0%.2Murad Mariam (2026)Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
Silica Skin Randomized Trial1 2 3 4 5 5 6 Plant-derived biomaterials have attracted increasing attention in recent years due to their unique structural, physicochemical, and functional properties, which offer innovative solutions across pharmaceutical, biomedical, and cosmetic applications [,,].2Murad Mariam (2026)Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
Silica Skin Randomized TrialResults According to the repeated-measures ANOVA, the control and study group had a significant reduction in follicular papule counts over time (all p Conclusion The combined formula effectively reduced follicular papules, improved skin hydration, decreased TEWL, and alleviated depressive symptoms in KP patients.2Liu F (2026)An Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
Silica Skin Randomized TrialObjective Keratosis pilaris (KP) is a common follicular keratotic skin disorder characterized by follicular papules and skin roughness, often accompanied by itching and inflammation, significantly affecting appearance and psychological health.2Liu F (2026)An Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
Silica Skin Randomized TrialMethods This 28-day prospective, open-label, randomized controlled study evaluated the effectiveness of a novel combined formula for KP treatment.2Liu F (2026)An Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicSilica Skin Randomized Trial
claimPrevious studies have demonstrated the successful loading and sustained release of bioactive molecules such as omega-3 fatty acids and vitamin D, with improved bioavailability attributed to mucoadhesion and controlled release mechanisms [].
evidence level2
citationMurad Mariam (2026)
sourceDouble-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
topicSilica Skin Randomized Trial
claimThis significantly reduces the risk of immunogenicity and has been supported by recent studies demonstrating minimal IgE reactivity and the good biocompatibility of sporopollenin-derived materials [,].
evidence level2
citationMurad Mariam (2026)
sourceDouble-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
topicSilica Skin Randomized Trial
claimCombustion elemental analysis found carbon: 67.9%; hydrogen: 79.19%; and nitrogen: 0.0%.
evidence level2
citationMurad Mariam (2026)
sourceDouble-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
topicSilica Skin Randomized Trial
claim1 2 3 4 5 5 6 Plant-derived biomaterials have attracted increasing attention in recent years due to their unique structural, physicochemical, and functional properties, which offer innovative solutions across pharmaceutical, biomedical, and cosmetic applications [,,].
evidence level2
citationMurad Mariam (2026)
sourceDouble-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
topicSilica Skin Randomized Trial
claimResults According to the repeated-measures ANOVA, the control and study group had a significant reduction in follicular papule counts over time (all p Conclusion The combined formula effectively reduced follicular papules, improved skin hydration, decreased TEWL, and alleviated depressive symptoms in KP patients.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicSilica Skin Randomized Trial
claimObjective Keratosis pilaris (KP) is a common follicular keratotic skin disorder characterized by follicular papules and skin roughness, often accompanied by itching and inflammation, significantly affecting appearance and psychological health.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.
topicSilica Skin Randomized Trial
claimMethods This 28-day prospective, open-label, randomized controlled study evaluated the effectiveness of a novel combined formula for KP treatment.
evidence level2
citationLiu F (2026)
sourceAn Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.

Source documents

  1. Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation
  2. An Innovative Formula for Keratosis Pilaris Treatment-A Randomized Controlled Study Based on the "Exfoliation-Dissolution-Repair" Concept.