topicSesame Lignans Blood Pressure Randomized Trial
claim1 2 Figure 1 3 4 p Lignans are a diverse class of naturally occurring polyphenolic compounds predominantly found in plants.
evidence level3
citationDas Gitishree (2026)
sourceMolecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review
topicSesame Lignans Blood Pressure Randomized Trial
claim8 9 10 11 12 13 14 15 Linum usitatissimum Sesamum indicum Lignans are mainly found in several plant-based foods, especially in seeds, whole grains, vegetables, and fruits, but they are also present in beverages, such as wine, tea, and coffee [].
evidence level3
citationDas Gitishree (2026)
sourceMolecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review
topicSesame Lignans Blood Pressure Randomized Trial
claimThe unique chemical structure of lignans allows them to act as phytoestrogens and antioxidants, contributing to a range of health benefits such as anti-inflammatory, anticancer, alleviating menopausal symptoms, reducing the risk of type 2 diabetes, and protecting cardiovascular health, among others [] ().
evidence level3
citationDas Gitishree (2026)
sourceMolecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review
topicSesame Lignans Blood Pressure Randomized Trial
claimStructurally, they consist of two phenylpropanoid units (C6-C3) linked by their central carbon atoms, forming a dimeric structure [].
evidence level3
citationDas Gitishree (2026)
sourceMolecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review
topicSesame Lignans Blood Pressure Randomized Trial
claim) supplementation may offer beneficial effects in modulating various cardiometabolic risk factors, although findings from clinical trials have been inconsistent.
evidence level4
citationKuo WH (2026)
sourceIntegrative Evidence on Sesame Supplementation for Cardiometabolic Risk Factors Relevant to Retinopathy.
topicSesame Lignans Blood Pressure Randomized Trial
claimSesame supplementation significantly reduced both systolic and diastolic blood pressure.
evidence level4
citationKuo WH (2026)
sourceIntegrative Evidence on Sesame Supplementation for Cardiometabolic Risk Factors Relevant to Retinopathy.
topicSesame Lignans Blood Pressure Randomized Trial
claimFurther-more, sesame intake was associated with a significant reduction in liver enzyme levels, particularly alanine aminotransferase (ALT).
evidence level4
citationKuo WH (2026)
sourceIntegrative Evidence on Sesame Supplementation for Cardiometabolic Risk Factors Relevant to Retinopathy.
topicSesame Lignans Blood Pressure Randomized Trial
claimBackground Cardiometabolic disorders, such as diabetes, hypertension, dyslipidemia, retinopathy, and non-alcoholic fatty liver disease, present significant health challenges globally.
evidence level4
citationKuo WH (2026)
sourceIntegrative Evidence on Sesame Supplementation for Cardiometabolic Risk Factors Relevant to Retinopathy.