evidence table
Selenium Thyroid Randomized Trial Evidence Table
Structured evidence table for Selenium Thyroid Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Selenium Thyroid Randomized Trial | Across studies, PBM was associated with reductions in thyroid autoantibodies, improvements in thyroid hormone indices, and decreases in LT4 dose requirements. | 1 | Berisha-Muharremi V (2026) | Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications. |
| Selenium Thyroid Randomized Trial | However, current evidence is limited by the small number of human studies, heterogeneous PBM protocols, and the frequent use of concomitant interventions such as selenium or vitamin D. | 1 | Berisha-Muharremi V (2026) | Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications. |
| Selenium Thyroid Randomized Trial | Chronic autoimmune thyroiditis (CAT), a common autoimmune thyroid disorder, is the leading cause of hypothyroidism in iodine-sufficient regions and is characterized by thyroid autoimmunity, chronic inflammation, and progressive structural thyroid changes. | 1 | Berisha-Muharremi V (2026) | Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications. |
| Selenium Thyroid Randomized Trial | Although levothyroxine (LT4) restores biochemical euthyroidism, it does not directly address the underlying autoimmune process, highlighting the need for adjunctive therapeutic strategies. | 1 | Berisha-Muharremi V (2026) | Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications. |
| Selenium Thyroid Randomized Trial | Graphical abstract A simplified figure displaying the main events leading to Hashimoto's thyroiditis and Grave's disease via Th1 and Th2 activation, and the potential sites of selenium (Se) action. | 4 | Duntas LH (2026) | The caprices of a trace element: selenium's considerable effects on Hashimoto's thyroiditis, though few on Graves' disease. |
| Selenium Thyroid Randomized Trial | (A) Activated by the dendritic cell, naïve helper T cells (CD4+ T cells) can mainly differentiate into two subsets, Th1 and Th2, which are crucial in orchestrating immune responses. | 4 | Duntas LH (2026) | The caprices of a trace element: selenium's considerable effects on Hashimoto's thyroiditis, though few on Graves' disease. |
Source documents