topicSelenium Thyroid Fatigue Randomized Trial
claimHowever, the existing body of evidence is substantially constrained by methodological limitations, including small study scales, predominantly single-center designs, and a lack of standardized protocols.
evidence level3
citationZhang Jing (2026)
sourceExploring the Comprehensive Treatment of Hashimoto’s Thyroiditis with Traditional Chinese Medicine from the Perspective of Modern Medicine
topicSelenium Thyroid Fatigue Randomized Trial
claimThis narrative review synthesizes contemporary understanding of the pathophysiology of HT and critically evaluates the scientific evidence supporting TCM interventions.
evidence level3
citationZhang Jing (2026)
sourceExploring the Comprehensive Treatment of Hashimoto’s Thyroiditis with Traditional Chinese Medicine from the Perspective of Modern Medicine
topicSelenium Thyroid Fatigue Randomized Trial
claimIn a relatively small cohort of 142 Polish patients, only seven polymorphisms were confirmed to be associated with HT, accounting for 5.5% of the overall variability.
evidence level3
citationZhang Jing (2026)
sourceExploring the Comprehensive Treatment of Hashimoto’s Thyroiditis with Traditional Chinese Medicine from the Perspective of Modern Medicine
topicSelenium Thyroid Fatigue Randomized Trial
claimCurrently, hormone replacement therapy is the predominant treatment approach for hypothyroidism.
evidence level3
citationZhang Jing (2026)
sourceExploring the Comprehensive Treatment of Hashimoto’s Thyroiditis with Traditional Chinese Medicine from the Perspective of Modern Medicine
topicSelenium Thyroid Fatigue Randomized Trial
claimIt is associated with elevated anti-thyroid peroxidase antibodies (TPOAb) and often anti-thyroglobulin antibodies (TgAb) ().
evidence level4
citationPersonius Lydia (2026)
sourceBeyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis
topicSelenium Thyroid Fatigue Randomized Trial
claimThe incidence of HT has increased over recent decades and is higher with advancing age, in women, and in iodine-sufficient populations (,).
evidence level4
citationPersonius Lydia (2026)
sourceBeyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis
topicSelenium Thyroid Fatigue Randomized Trial
claimWet cupping was associated with a statistically significant reduction in anti-thyroid autoantibody levels and a decrease in TSH despite stable thyroid hormone dosing ().
evidence level4
citationPersonius Lydia (2026)
sourceBeyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis
topicSelenium Thyroid Fatigue Randomized Trial
claim1 2 3 4 Hashimoto’s thyroiditis (HT) is an autoimmune disorder that has been well documented as the leading cause of hypothyroidism and the most common form of thyroiditis ().
evidence level4
citationPersonius Lydia (2026)
sourceBeyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis