Selenium Thyroid Autoimmunity Randomized Trial Evidence Table

Structured evidence table for Selenium Thyroid Autoimmunity Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Selenium Thyroid Autoimmunity Randomized TrialSubclinical hypothyroidism has been associated with metabolic disturbances, increased cardiovascular risk, and reduced quality of life, highlighting the need for effective management strategies [,].1Stanchev Pavel (2026)Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis
Selenium Thyroid Autoimmunity Randomized TrialIt is thought to enhance TSH signaling and support thyroid hormone synthesis, with emerging clinical evidence suggesting a beneficial effect on thyroid function parameters [].1Stanchev Pavel (2026)Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis
Selenium Thyroid Autoimmunity Randomized TrialDespite these promising findings, the available evidence remains limited, and there is currently no consensus regarding the clinical benefit of combination therapy over selenium alone.1Stanchev Pavel (2026)Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis
Selenium Thyroid Autoimmunity Randomized Trial1 2 3 2 3 Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disorder and the leading cause of hypothyroidism in iodine-sufficient regions worldwide [].1Stanchev Pavel (2026)Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis
Selenium Thyroid Autoimmunity Randomized TrialAs a result, many patients will experience ongoing autoimmunity, abnormal thyroid morphology, or residual symptoms after their hormone replacement is optimized [,].1Berisha-Muharremi Venera (2026)Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications
Selenium Thyroid Autoimmunity Randomized Trial17 18 In the thyroid gland, the increased perfusion may improve the viability of thyroid follicular cells, the synthesis of hormones, and tissue regeneration [,].1Berisha-Muharremi Venera (2026)Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications
Selenium Thyroid Autoimmunity Randomized Trial19 Figure 1 Collectively, these molecular and microvascular mechanisms provide biologic plausibility for the therapeutic effects reported in patients treated with PBM/LLLT for CAT (including improved thyroid hormone indices, reduced levels of thyroid autoantibodies, and reduced doses of LT4) [] ().1Berisha-Muharremi Venera (2026)Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications
Selenium Thyroid Autoimmunity Randomized Trial1 2 3 4 5 6 7 CAT, also referred to in the literature as HT, is the most prevalent autoimmune endocrine disease and one of the primary causes of hypothyroidism in areas with sufficient iodine supply worldwide [,].1Berisha-Muharremi Venera (2026)Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications

Source documents

  1. Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis
  2. Photobiomodulation Therapy in Chronic Autoimmune Thyroiditis: A Systematic Review of Molecular Mechanisms and Clinical Applications