evidence table

Selenium Acne Randomized Trial Evidence Table

Structured evidence table for Selenium Acne Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Selenium Acne Randomized TrialStatistical analysis was performed using STATA 14.2, with P Results In comparison with BPO, NAC treatment led to a significantly greater improvement in CADI scores (MD=-3.60, 95% CI: -4.26 - -2.95, P Conclusion Topical NAC combined with doxycycline was significantly more effective than BPO-doxycycline in acne treatment, with minimal adverse effects.2Parvizi MM (2026)Comparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
Selenium Acne Randomized TrialIntroduction Acne vulgaris is a prevalent skin disorder, especially among adolescents.2Parvizi MM (2026)Comparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
Selenium Acne Randomized TrialWhile topical retinoid and benzoyl peroxide (BPO) are standard treatments, their side effects often decrease patient adherence.2Parvizi MM (2026)Comparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
Selenium Acne Randomized TrialIn conclusion, these findings suggest that 8 weeks of probiotic supplementation may alleviate oxidative stress, modulate certain hormonal factors, and reduce inflammation in women with PCOS.2Shirani M (2025)Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.
Selenium Acne Randomized TrialPolycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women.2Shirani M (2025)Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.
Selenium Acne Randomized TrialThis study investigates the impact of 8-week supplementation with two probiotic strains, Lactobacillus helveticus and Bifidobacterium longum, on hormonal status, oxidative stress, and clinical symptoms in women with PCOS.2Shirani M (2025)Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.
topicSelenium Acne Randomized Trial
claimStatistical analysis was performed using STATA 14.2, with P Results In comparison with BPO, NAC treatment led to a significantly greater improvement in CADI scores (MD=-3.60, 95% CI: -4.26 - -2.95, P Conclusion Topical NAC combined with doxycycline was significantly more effective than BPO-doxycycline in acne treatment, with minimal adverse effects.
evidence level2
citationParvizi MM (2026)
sourceComparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
topicSelenium Acne Randomized Trial
claimIntroduction Acne vulgaris is a prevalent skin disorder, especially among adolescents.
evidence level2
citationParvizi MM (2026)
sourceComparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
topicSelenium Acne Randomized Trial
claimWhile topical retinoid and benzoyl peroxide (BPO) are standard treatments, their side effects often decrease patient adherence.
evidence level2
citationParvizi MM (2026)
sourceComparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
topicSelenium Acne Randomized Trial
claimIn conclusion, these findings suggest that 8 weeks of probiotic supplementation may alleviate oxidative stress, modulate certain hormonal factors, and reduce inflammation in women with PCOS.
evidence level2
citationShirani M (2025)
sourceEffects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.
topicSelenium Acne Randomized Trial
claimPolycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women.
evidence level2
citationShirani M (2025)
sourceEffects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.
topicSelenium Acne Randomized Trial
claimThis study investigates the impact of 8-week supplementation with two probiotic strains, Lactobacillus helveticus and Bifidobacterium longum, on hormonal status, oxidative stress, and clinical symptoms in women with PCOS.
evidence level2
citationShirani M (2025)
sourceEffects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.

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Source documents

  1. Comparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial.
  2. Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial.