topicSea Buckthorn Skin Randomized Trial
claimHippophae rhamnoides Elaeagnaceae α β γ α β γ p 1 2 3 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 3 18 19 Sea buckthorn (SB), also known as, is a deciduous shrub rich in nutrients belonging to the family, mostly found in coastal areas, river banks and mountainous zones in Eastern Europe and Asia [].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Randomized Trial
claimSB has a long history as a therapeutic substance, being used to treat different skin-associated health problems (it was used for skin repair, UV-photoprotection, in psoriasis, allergic and atopic dermatitis, acne, ichthyosis) for thousands of years in several different cultures [,,].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Randomized Trial
claimIts bioactive compounds (flavonoids, carotenoids, and unsaturated fatty acids) also contribute to immune regulation and protection against vascular dysfunction associated with chronic inflammation and oxidative stress [,].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Randomized Trial
claimReview approach: This review covers studies on fatty acid composition, minor bioactive compounds, antioxidant and anti-inflammatory activities, lipid metabolism-related effects, and the valorization of processing by-products, with evidence primarily derived from in vitro and in vivo studies.
evidence level3
citationJiang X (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization.
topicSea Buckthorn Skin Randomized Trial
claimHowever, current evidence is largely based on experimental studies, and further research is needed to clarify the mechanisms of action, bioavailability, dose-response relationships, and clinical efficacy.
evidence level3
citationJiang X (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization.
topicSea Buckthorn Skin Randomized Trial
claimBackground This review summarizes the current knowledge on the composition, bioactive constituents, health-related effects, and by-product utilization of sea buckthorn ( Hippophaë rhamnoides L.) seed and pulp oils.
evidence level3
citationJiang X (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization.