topicSea Buckthorn Skin Aging Randomized Trial
claimHippophae rhamnoides Elaeagnaceae α β γ α β γ p 1 2 3 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 3 18 19 Sea buckthorn (SB), also known as, is a deciduous shrub rich in nutrients belonging to the family, mostly found in coastal areas, river banks and mountainous zones in Eastern Europe and Asia [].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Aging Randomized Trial
claimSB has a long history as a therapeutic substance, being used to treat different skin-associated health problems (it was used for skin repair, UV-photoprotection, in psoriasis, allergic and atopic dermatitis, acne, ichthyosis) for thousands of years in several different cultures [,,].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Aging Randomized Trial
claimIts bioactive compounds (flavonoids, carotenoids, and unsaturated fatty acids) also contribute to immune regulation and protection against vascular dysfunction associated with chronic inflammation and oxidative stress [,].
evidence level1
citationHincu Maria Andrada (2026)
sourceRosacea and Hippophae rhamnoides : A Phytonutrient Approach to Skin Repair (The Systematic Review)
topicSea Buckthorn Skin Aging Randomized Trial
claimCurrent challenges include a lack of standardization in extraction methods, a limited mechanistic understanding of bioactive interactions, and insufficient clinical evidence to substantiate health claims.
evidence level3
citationJiang Xiaojing (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization
topicSea Buckthorn Skin Aging Randomized Trial
claimAlthough this concentration is notably lower than the 30–35% typically found in tropical oils such as palm or coconut oil, PA remains integral to the unique therapeutic efficacy of SBSO [].
evidence level3
citationJiang Xiaojing (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization
topicSea Buckthorn Skin Aging Randomized Trial
claimCollectively, these components facilitate barrier repair without the adverse effects typically associated with corticosteroids [].
evidence level3
citationJiang Xiaojing (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization
topicSea Buckthorn Skin Aging Randomized Trial
claimHippophae rhamnoides 1 2 3 Figure 1 Sea buckthorn (L.) is a hardy shrub widely distributed across Eurasia and is recognized as an important functional plant resource.
evidence level3
citationJiang Xiaojing (2026)
sourceFrom Nutritional Profile to Circular Bioeconomy: A Review of Sea Buckthorn Oil and By-Product Valorization